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Bax channel blocker(BAI-1)

  Cat. No.:  DC12663   Featured
Chemical Structure
335165-68-9
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More than 5000 active chemicals with high quality for research!
Field of application
Bax channel blocker is a potent inhibitor of Bax-mediated mitochondrial cytochrome C release (IC50 = 0.52 μM). Suggested to inhibit Bax channel formation/activity.
Cas No.: 335165-68-9
Chemical Name: BAI1 inhibitor
Synonyms: 3,6-DIBROMO-ALPHA-(1-PIPERAZINYLMETHYL)-9H-CARBAZOLE-9-ETHANOL DIHYDROCHLORIDE;1-(3,6-dibromocarbazol-9-yl)-3-piperazin-1-ylpropan-2-ol,dihydrochloride;3,6-DibroMo-α-(1-piperazinylMethyl)-9H-carbazole-9-ethanoldihydrochloride;Bax channel blocker;BAI1
SMILES: OC(CN1CCNCC1)CN2C3=C(C4=C2C=CC(Br)=C4)C=C(Br)C=C3
Formula: C19H21Br2N3O
M.Wt: 467.205
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: BAI1 is a direct allosteric inhibitor of BAX.
References: [1]. Garner TP, et al. Small-molecule allosteric inhibitors of BAX. Nat Chem Biol. 2019 Apr;15(4):322-330.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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