天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

  1. Anti-infection Cell Cycle/DNA Damage
  2. Bacterial Topoisomerase Antibiotic
  3. Gatifloxacin mesylate

Gatifloxacin mesylate  (Synonyms: 甲磺酸加替沙星; AM-1155 mesylate; BMS-206584 mesylate; PD135432 mesylate)

目錄號: HY-10581B
產品使用指南 技術支持

Gatifloxacin mesylate (AM-1155 mesylate) 是一種有效的氟喹諾酮類抗生素 (antibiotic),具有廣譜抗菌活性。Gatifloxacin mesylate (AM-1155 mesylate) 可抑制細菌 II 型拓撲異構酶 (type II topoisomerases) (IC50=13.8 μg/ml; 金黃色葡萄球菌拓撲異構酶 IV) 和大腸桿菌 DNA 解旋酶 (IC50=0.109 μg/ml)。Gatifloxacin mesylate (AM-1155 mesylate) 在動物模型中,可用于細菌性結膜炎研究。

MCE 的所有產品僅用作科學研究或藥證申報,我們不為任何個人用途提供產品和服務

Gatifloxacin mesylate Chemical Structure

Gatifloxacin mesylate Chemical Structure

CAS No. : 316819-28-0

1.  客戶無需承擔相應的運輸費用。

2.  同一機構(單位)同一產品試用裝僅限申領一次,同一機構(單位)一年內

     可免費申領三個不同產品的試用裝。

3.  試用裝只面向終端客戶

規(guī)格 是否有貨
50 mg   詢價  
100 mg   詢價  
250 mg   詢價  

* Please select Quantity before adding items.

Gatifloxacin mesylate 的其他形式現(xiàn)貨產品:

Other Forms of Gatifloxacin mesylate:

  • 生物活性

  • 純度 & 產品資料

  • 參考文獻

生物活性

Gatifloxacin mesylate (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin mesylate inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50 = 0.109 μg/ml)[1]. Gatifloxacin mesylate can be used to treat bacterial conjunctivitis in vivo.

IC50 & Target[1]

Quinolone

 

Topoisomerase II

36.7 μM (IC50)

體外研究
(In Vitro)

Gatifloxacin mesylate is against S. aureus MS5935 topoisomerase IV, E. coli NIHJ JC-2 DNA gyrase and HeLa cell topoisomerase II with IC50 values of 13.8 μg/ml, 0.109 μg/ml, and 265 μg/ml, respectively[1].
Gatifloxacin mesylate is against S. aureus MS5935 topoisomerase IV, E. coli NIHJ JC-2 DNA gyrase and HeLa cell topoisomerase II with MIC values of 0.05 μg/ml, 0.0063 μg/ml, and 122 μg/ml, respectively[1].
Gatifloxacin mesylate exhibits antibacterial activities for wild-type strains (MS5935, MS5952, MR5867 and MR6009) the first-, second-, third-, and fourth-step mutants with MIC values of 0.05 to 0.10 μg/ml, 0.20 μg/ml, 1.56 to 3.13 μg/ml, 1.56 to 6.25 μg/ml, and 50 to 200 μg/ml, respectively. Gatifloxacin mesylate displays the most potent activity against the second- and third-step mutants (MS5952, MR5867 and MR6009) except for the second-step mutant of strain MS5935[2].
Gatifloxacin mesylate has potent activity against norA transformant NY12 (MIC, 0.39 μg/ml)[2].
Gatifloxacin mesylate (20-100 μM; 72 hours) significantly decreases insulin content to 60% at Day 1, and continues to be reduced to 50.1% and 44.7% at Day 3 by 20 μM and 100 μM Gatifloxacin mesylate, respectively[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

體內研究
(In Vivo)

Gatifloxacin mesylate (subcutaneous injection; 100 mg/kg; 3 times a day; 30 days) significantly decreases the number of lesions in mouse footpad with Nocardia brasiliensis[4].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female BALB/c mice with Nocardia brasiliensis in the right hind footpad.
Dosage: 100 mg/kg
Administration: Subcutaneous injection; 3 times a day; 30 days
Result: Reduced the production of lesions in mice.
Clinical Trial
分子量

471.50

Formula

C20H26FN3O7S

CAS 號
中文名稱

甲磺酸加替沙星

運輸條件

Room temperature in continental US; may vary elsewhere.

儲存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

純度 & 產品資料
參考文獻
  • 摩爾計算器

  • 稀釋計算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

您最近查看的產品:

Your information is safe with us. * Required Fields.

   產品名稱:

 

* 需求量:

* 客戶姓名:

 

* Email:

* 電話:

 

* 公司或機構名稱:

   留言給我們:

Bulk Inquiry

Inquiry Information

產品名稱:
Gatifloxacin mesylate
目錄號:
HY-10581B
需求量: