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  1. Apoptosis Metabolic Enzyme/Protease Immunology/Inflammation NF-κB
  2. Apoptosis Endogenous Metabolite Reactive Oxygen Species (ROS)
  3. Malvidin-3-galactoside chloride

Malvidin-3-galactoside chloride  (Synonyms: 氯化錦葵色素-3-O-半乳糖苷)

目錄號: HY-N6623 純度: 99.63%
COA 產(chǎn)品使用指南 技術支持

Malvidin-3-galactoside chloride 是一種花青素單體,可誘導肝細胞癌 (HCC) 細胞周期停滯和凋亡。Malvidin-3-galactoside chloride 抑制 ROS 的產(chǎn)生和積累。Malvidin-3-galactoside chloride 具有抗腫瘤功能。

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Malvidin-3-galactoside chloride Chemical Structure

Malvidin-3-galactoside chloride Chemical Structure

CAS No. : 30113-37-2

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Other Forms of Malvidin-3-galactoside chloride:

  • 生物活性

  • 純度 & 產(chǎn)品資料

  • 參考文獻

生物活性

Malvidin-3-galactoside chloride, an anthocyanin monomer, induces hepatocellular carcinoma (HCC) cells cycle arrest and apoptosis. Malvidin-3-galactoside chloride inhibits the production and accumulation of ROS. Malvidin-3-galactoside chloride has anti-tumor function[1].

IC50 & Target

Human Endogenous Metabolite

 

體外研究
(In Vitro)

Malvidin-3-galactoside chloride (50, 100, 200 μg/mL; for 24, 48, 72 h) displays obvious cytotoxicity on Huh-7 cells and has no significant effect with 50 and 100 μg/mL for 48 h. Malvidin-3-galactoside chloride has a notable cytotoxic effect against Huh-7 cells at 72 h[1].
Malvidin-3-galactoside chloride (50-200 μg/mL) arrests the cells in the S phase, accompanied by the cells in the G1 phase decreased, and the cells in the S phase increased[1].
Malvidin-3-galactoside chloride (50-200 μg/mL; for 72 h) induces cell apoptosis in Huh-7 cells[1].
Malvidin-3-galactoside chloride (50-200 μg/mL; for 72 h) markedly increased the levels of caspase-3, cleaved-caspase-3 and cleaved-PARP in a dose-dependent manner[1].
Malvidin-3-galactoside chloride (50-200 μg/mL; for 12 h) inhibits the production and accumulation of ROS[1].
Malvidin-3-galactoside chloride (50-200 μg/mL; for 12 h) dramatically reduces the level of phosphorylation ERK (p-ERK) in a dose-dependent manner. Malvidin-3-galactoside chloride with 200 μg/mL markedly increases the phosphorylation level of p38 and JNK (p-p38 and p-JNK)[1].
Malvidin-3-galactoside chloride (50-200 μg/mL; for 12 h) inhibits the migration and invasion in Huh-7 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

528.89

Formula

C23H25ClO12

CAS 號
性狀

固體

顏色

Brown to black

中文名稱

氯化錦葵色素-3-O-半乳糖苷

結構分類
初始來源
運輸條件

Room temperature in continental US; may vary elsewhere.

儲存方式

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

純度 & 產(chǎn)品資料
參考文獻
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱:
Malvidin-3-galactoside chloride
目錄號:
HY-N6623
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