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CANDESARTAN-D4

CANDESARTAN-D4 Struktur
1346604-70-3
CAS-Nr.
1346604-70-3
Englisch Name:
CANDESARTAN-D4
Synonyma:
CV-11974-d4;CANDESARTAN-D4;[2H4]-Candesartan;Candesartan M1-d4;Candesartan D4 (CV-11974 D4);2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1-(phenyl-d4)-1'-phenyl]-4-yl]Methyl]-1H-benziMidazole-7-carboxylic Acid;1-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl-2,3,5,6-d4)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylic acid;1-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl-2,3,5,6-d4)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylic acid;2-ethoxy-1-{[2'-(1H-1,2,3,4-tetrazol-5-yl)(2,3,5,6-2H?)-[1,1'-biphenyl]-4-yl]methyl}-1H-1,3-benzodiazole-7-carboxylic acid;Candesartan D4Q: What is Candesartan D4 Q: What is the CAS Number of Candesartan D4 Q: What is the storage condition of Candesartan D4
CBNumber:
CB4477701
Summenformel:
C24H16D4N6O3
Molgewicht:
444.48
MOL-Datei:
Mol file

CANDESARTAN-D4 Eigenschaften

Schmelzpunkt:
151-157°C
storage temp. 
-20°C Freezer
L?slichkeit
DMSO (Slightly), Methanol (Slightly, Heated)
Aggregatzustand
Solid
Farbe
White to Off-White
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H360 Kann die Fruchtbarkeit beeintr?chtigen oder das Kind im Mutterleib sch?digen. Fertility (Fruchtbarkeit) Kategorie 1 Achtung GHS hazard pictogramssrc="/GHS08.jpg" width="20" height="20" />
Sicherheit
P201 Vor Gebrauch besondere Anweisungen einholen.
P202 Vor Gebrauch alle Sicherheitshinweise lesen und verstehen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P308+P313 BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen.
P405 Unter Verschluss aufbewahren.
P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

CANDESARTAN-D4 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Candesartan-d4 is intended for use as an internal standard for the quantification of candesartan by GC- or LC-MS. Candesartan is an antagonist of the angiotensin II type 1 (AT1) receptor (Kis = 0.17, 0.12, and 0.12 nM for human AT1, rat AT1A, and rat AT1B recombinant receptors, respectively) and an active metabolite of the prodrug candesartan cilexitil (Item No. 10489). It is selective for AT1 over AT2 receptors (Ki = 26,500 nM for the human recombinant AT2 receptor). It inhibits angiotensin II-induced contraction of isolated rabbit aortic strips and increases in blood pressure in rats following intravenous administration (ID50 = 0.033 mg/kg). Formulations containing candesartan have been used in the treatment of hypertension and heart failure.

Chemische Eigenschaften

CANDESARTAN-D4 is White to Off-White Solid

Verwenden

CANDESARTAN-D4 is an angiotensin II type-1 receptor antagonist. Used in treatment of congestive heart failure. Antihypertensive.

CANDESARTAN-D4 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

CANDESARTAN-D4 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 65)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
BOC Sciences 		+1-631-485-4226
inquiry@bocsci.com United States 19552 58
TargetMol Chemicals Inc. 		+17819995354
 marketing@targetmol.com United States 32281 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38665 58
Aladdin Scientific
tp@aladdinsci.com United States 52924 58
Guangzhou CATO Research Chemicals Inc. 		+86-020-81960175-617 +8615602392859
 Intermediate@cato-chem.com China 6335 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131957 58
J & K SCIENTIFIC LTD. 18210857532
 jkinfo@jkchemical.com China 96815 76
Chemsky（shanghai）International Co.,Ltd. 021-50135380
shchemsky@sina.com China 32321 50
MedChemexpress LLC 021-58955995
sales@medchemexpress.cn United States 4861 58
Cato Research Chemicals Inc. 020-81960175
min.he@cato-chem.com China 1955 55

1346604-70-3()Verwandte Suche:

  • 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1-(phenyl-d4)-1'-phenyl]-4-yl]Methyl]-1H-benziMidazole-7-carboxylic Acid
  • Candesartan M1-d4
  • CV-11974-d4
  • CANDESARTAN-D4
  • [2H4]-Candesartan
  • Candesartan D4Q: What is Candesartan D4 Q: What is the CAS Number of Candesartan D4 Q: What is the storage condition of Candesartan D4
  • Candesartan D4 (CV-11974 D4)
  • 1-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl-2,3,5,6-d4)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylic acid
  • 2-ethoxy-1-{[2'-(1H-1,2,3,4-tetrazol-5-yl)(2,3,5,6-2H?)-[1,1'-biphenyl]-4-yl]methyl}-1H-1,3-benzodiazole-7-carboxylic acid
  • 1-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl-2,3,5,6-d4)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylic acid
  • 1346604-70-3
  • C24H16D4N6O3
  • Aromatics
  • Bases & Related Reagents
  • Intermediates & Fine Chemicals
  • Isotope Labelled Compounds
  • Nucleotides
  • Pharmaceuticals
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