價格 | 詢價 | ||
包裝 | 20μl | 50μl | 100μl |
最小起訂量 | 1μl |
發(fā)貨地 | 上海 |
更新日期 | 2025-05-28 |
中文名稱:PLPP2抗體 | 英文名稱:Rabbit Polyclonal PLPP2 Antibody |
品牌: 艾普蒂 | 產(chǎn)地: 武漢 |
保存條件: Stored at -20°C for 7467 year. Avoid repeated freeze / thaw cycles. | 產(chǎn)品類別: 抗體 |
重組: 否 | 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA |
種屬反應(yīng)性: Human,Mouse,Rat | 宿主: Rabbit |
偶聯(lián)物: 無 | 靶點: PLPP2 |
WB | 咨詢技術(shù) | Human,Mouse,Rat |
IF | 咨詢技術(shù) | Human,Mouse,Rat |
IHC | 1/50-1/200 | Human,Mouse,Rat |
ICC | 技術(shù)咨詢 | Human,Mouse,Rat |
FCM | 咨詢技術(shù) | Human,Mouse,Rat |
Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
Aliases | LPP2; PAP-2c; PAP2-g; PPAP2C |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthetic peptide of human PLPP2 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P13749(PLPP2 Antibody) at dilution 1/50. (Original magnification: ×200)
The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P13749(PLPP2 Antibody) at dilution 1/50. (Original magnification: ×200)
以下是關(guān)于PLPP2抗體的參考文獻(xiàn)示例(注:部分文獻(xiàn)為假設(shè)性示例,實際引用時需核實):
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1. **"PLPP2 regulates lipid signaling and promotes cancer metastasis through phosphatidic acid modulation"**
*Authors: Zhang Y, Wang L, Chen H*
摘要:本研究通過開發(fā)一種高特異性PLPP2單克隆抗體,揭示了PLPP2在乳腺癌轉(zhuǎn)移中的作用??贵w用于免疫印跡和免疫熒光實驗,證實PLPP2通過調(diào)控磷脂酸代謝促進腫瘤細(xì)胞侵襲。
2. **"A novel monoclonal antibody targeting PLPP2 for functional characterization in adipocyte differentiation"**
*Authors: Tanaka K, Suzuki R, Yamamoto M*
摘要:作者開發(fā)了一種針對PLPP2的新型抗體,并驗證其在流式細(xì)胞術(shù)中的適用性。研究發(fā)現(xiàn)PLPP2在脂肪細(xì)胞分化中通過調(diào)節(jié)脂質(zhì)穩(wěn)態(tài)發(fā)揮關(guān)鍵作用,抗體阻斷實驗表明其活性缺失抑制分化進程。
3. **"Antibody-based profiling of PLPP2 expression in neurodegenerative disorders"**
*Authors: Müller S, Braun A, Jansen S*
摘要:利用PLPP2多克隆抗體對阿爾茨海默癥患者腦組織進行免疫組化分析,發(fā)現(xiàn)PLPP2在病變區(qū)域的表達(dá)顯著上調(diào),提示其可能與神經(jīng)炎癥及脂質(zhì)代謝異常相關(guān)。
4. **"PLPP2 inhibition via neutralizing antibodies attenuates hepatic steatosis in mouse models"**
*Authors: Gupta R, Patel V, Lee T*
摘要:研究通過中和性PLPP2抗體在小鼠模型中抑制其活性,證明PLPP2在非酒精性脂肪肝(NAFLD)中的關(guān)鍵作用。抗體治療顯著減少肝臟脂質(zhì)積累,為靶向治療提供新策略。
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**注意**:以上文獻(xiàn)為示例性質(zhì),實際研究中需根據(jù)具體需求檢索真實數(shù)據(jù)庫(如PubMed、Web of Science)并核對原文信息。
The PLPP2 (Phospholipid Phosphatase 2) antibody is a tool used to detect and study the PLPP2 protein, a member of the lipid phosphate phosphatase (LPP) family. PLPP2. also known as PPAP2B or LPP3. is a transmembrane enzyme that hydrolyzes phosphatidic acid, lysophosphatidic acid, and other lipid phosphates, regulating lipid signaling and metabolism. It plays critical roles in cellular processes such as membrane integrity maintenance, cell migration, and angiogenesis. Dysregulation of PLPP2 has been implicated in pathologies like cancer, cardiovascular diseases, and metabolic disorders, with studies linking its altered expression to tumor progression and atherosclerosis.
The PLPP2 antibody enables researchers to investigate the protein's expression, localization, and function in various tissues and disease models. It is widely used in techniques like Western blotting, immunohistochemistry, and immunofluorescence. Recent research highlights its importance in modulating Wnt/β-catenin signaling and maintaining lipid homeostasis, suggesting therapeutic potential. By facilitating precise detection of PLPP2. this antibody contributes to understanding its role in health and disease, aiding biomarker discovery and mechanistic studies. Its specificity and reliability are validated across experimental platforms, making it essential for exploring lipid-mediated signaling pathways.
成立日期 | 2024-07-02 (2年) | 注冊資本 | 20萬人民幣 |
員工人數(shù) | 1-10人 | 年營業(yè)額 | ¥ 100萬以內(nèi) |
主營行業(yè) | 抗體,植物生物技術(shù),細(xì)胞培養(yǎng),蛋白組學(xué) | 經(jīng)營模式 | 貿(mào)易,工廠,試劑,定制,服務(wù) |
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