Changsha Staherb Natural Ingredients Co., LTD.

Product Introduction

α-Mangostin (6147-11-1) is a xanthone natural product that has historically been used in traditional folk medicine.

1 It is a potent agonist of human STING (Stimulator of Interferon Genes) and also weakly activates mouse STING.

2 Induces IFN-β production and repolarizes human monocyte-derived M2 macrophages to M1. Improves insulin secretion and protects INS-1 cells from streptozotocin-induced damage.

3 Suppresses the metastasis of human renal carcinoma cells.4 Synergizes with kinase inhibitors in suppression of proliferation of SK-MEL-2 malignant melanoma cells

Product Physicochemical Property

Product Name Mangosteen peel extract Mangostin

Part of used Fruit peel

Test Method HPLC 

Active ingredient Mangostin

Molecular Formula C24H26O6

Molecular Weight 410.46

Specs Available 1%-98%

CAS NO. 6147-11-1

Appearance Brown yellow fine powder

Solubility Soluble in ethyl alcohol

Odour Characteristic

Particle Size 100% pass 80 mesh

Shelf Life 24 months

Certificate COA, Kosher

Function

Mangostin derivative isolated from mangosteen (Garcinia mangostana). Antioxidant and anti-inflammatory. αmangostin has been shown to induce apoptosis via the mitochondrial pathway, reduce cell proliferation and inhibit tumorigenesis Application

1. Functional foods and beverages, healthcare product

2. Cosmetics,

3. Feed additive,

4. Medicine

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