1,2-DIBROMOETHYLENE synthesis
- Product Name:1,2-DIBROMOETHYLENE
- CAS Number:590-12-5
- Molecular formula:C2H2Br2
- Molecular Weight:185.85
74-86-2
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590-12-5
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Yield:590-12-5 73%
Reaction Conditions:
with bromine in dichloromethane;N,N-dimethyl-formamide at -5 - 20; for 4 h;
Steps:
1.1-4.1 Step 1: Preparation of trans-1,2-dibromoethylene
In a 250mL three-necked flask, pass acetylene (2.6g, 100mmol) into 20mL dichloromethane, add DMF (1.3g, 18mmol), dropwise add bromine dissolved in 100mL dichloromethane (-5 ~ 0 ) ( 19.2g, 120mmol) solution, dropwise, stirring at room temperature for 4 hours. After the reaction is completed, the sodium thiosulfate solution is quenched, the layers are separated, the organic layer is washed with water, dried over anhydrous sodium sulfate, and purified by atmospheric distillation to obtain product 1. , 2-Dibromoethylene 13.6g (107-110 ° C fraction), yield 73%. GC and 1HNMR detection: purity 98.6%, E/Z ratio 96/4.
References:
CN107602337,2020,B Location in patent:Paragraph 0017-0019; 0022-0024; 0026-0028; 0030-0032
