ETHYL 3-(3-CHLORO-2,4,5-TRIFLUOROPHENYL)-3-OXOPROPANOATE synthesis
- Product Name:ETHYL 3-(3-CHLORO-2,4,5-TRIFLUOROPHENYL)-3-OXOPROPANOATE
- CAS Number:101987-86-4
- Molecular formula:C11H8ClF3O3
- Molecular Weight:280.63
101513-77-3
259 suppliers
$20.39/1g
101987-86-4
152 suppliers
$6.00/1g
Yield:-
Steps:
Multi-step reaction with 3 steps
1.1: thionyl chloride / N,N-dimethyl-formamide / 4 h / Reflux
2.1: magnesium / tetrachloromethane; ethanol / 3.25 h / Reflux
2.2: 2.33 h / -10 °C
3.1: toluene-4-sulfonic acid / water / 5 h / Reflux
References:
Huang, Ju;Wang, Minghua;Wang, Bin;Wu, Zhaoyang;Liu, Mingliang;Feng, Lianshun;Zhang, Jun;Li, Xiaoning;Yang, Yang;Lu, Yu [Bioorganic and Medicinal Chemistry Letters,2016,vol. 26,# 9,p. 2262 - 2267]
101513-78-4
57 suppliers
$31.80/1gm:
101987-86-4
152 suppliers
$6.00/1g
6148-64-7
405 suppliers
$5.00/10g
101513-78-4
57 suppliers
$31.80/1gm:
101987-86-4
152 suppliers
$6.00/1g