2-CHLORODIBENZO-P-DIOXIN synthesis
- Product Name:2-CHLORODIBENZO-P-DIOXIN
- CAS Number:39227-54-8
- Molecular formula:C12H7ClO2
- Molecular Weight:218.64
31928-44-6
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$6.00/1g
120-80-9
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$13.00/25g
39227-54-8
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$1478.40/10ML
Yield:39227-54-8 70%
Reaction Conditions:
with copper;potassium carbonate in N,N-dimethyl-formamide at 150; for 24 h;
Steps:
1
3.15 g (10 mmol) of 2-bromo-4-chloro-1-iodinebenzene, 1.10 g (10 mmol) of 1,2-benzenediol, 0.3 g (5 mmol) of Cu, and 2.76 g (20 mmol) of K2CO3 were dissolved in 50 ml of DMF, and then, the mixed solution was stirred at a temperature of 150° C. for 24 hours. After the reaction solution was cooled to room temperature, 60 ml of water was added thereto, and an extraction process was performed thereon three times by using 60 ml of ethylether. An organic layer collected therefrom was dried by using magnesium sulfate, and residual obtained by evaporating a solvent therefrom was separation-purified by silica gel chromatography to obtain 1.526 g (yield: 70%) of Intermediate A.
References:
US2018/13076,2018,A1 Location in patent:Paragraph 0351; 0352
54536-18-4
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39227-53-7
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$165.00/1mg
39227-54-8
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$1478.40/10ML
33857-26-0
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$502.18/5MG
262-12-4
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$37.00/100mg
39227-54-8
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$1478.40/10ML
29446-15-9
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$140.00/5mg
262-12-4
110 suppliers
$37.00/100mg
39227-54-8
8 suppliers
$1478.40/10ML
262-12-4
110 suppliers
$37.00/100mg
39227-54-8
8 suppliers
$1478.40/10ML