3,3',4,4'-TETRAMETHYL BENZOPHENONE synthesis
- Product Name:3,3',4,4'-TETRAMETHYL BENZOPHENONE
- CAS Number:4659-48-7
- Molecular formula:C17H18O
- Molecular Weight:238.32
Yield: 93.8%
Reaction Conditions:
with iron(III) chloride;sulfuric acid at 5 - 10; for 0.8 h;Reagent/catalyst;Temperature;
Steps:
2
A mixture of o-xylene 106g (0.998mol), ferric chloride 130g (0.785mol) and the mass concentration of 98% concentrated sulfuric acid 10g added to the reaction flask. The 160g (1.029mol) of carbon tetrachloride was added dropwise to the reaction flask. After completion of the dropwise addition, incubated 0.8 hours at a temperature of 5-10 °C condition, the disappearance of the HPLC detector o-xylene, the reaction can be terminated.Washed with water and ferric chloride excess concentrated sulfuric acid, until pH = 4 ~ 5, a reduced pressure to recover the remaining carbon tetrachloride to give an oil 160g.500g residual oil was recrystallized from ethanol, to give 3,3',4,4'-tetramethylbenzophenone 111.6g, 93.8% yield, 98.4% purity.
References:
JIANGSU AOLUNDA HIGH-TECH INDUSTRY CO., LTD;WAN, LIBING;CHEN, HAIQUN;ZHANG, YIN;CHEN, PANQIANG;CHEN, LYU CN104557501, 2016, B Location in patent:Paragraph 0024; 0025
5973-71-7
350 suppliers
$10.00/25g
583-71-1
177 suppliers
$13.43/1gm:
4659-48-7
14 suppliers
inquiry
95-47-6
609 suppliers
$10.00/25g
4659-48-7
14 suppliers
inquiry
6578-78-5
0 suppliers
inquiry
4659-48-7
14 suppliers
inquiry