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141524-73-4

(4-bromo-1-methyl-1H-imidazol-5-yl)methanol synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: sodium nitrite; nitric acid / water / 14 h / 0 - 23 °C / pH 9 / Inert atmosphere
2: N-Bromosuccinimide / N,N-dimethyl-formamide / -20 °C / Inert atmosphere

References:

Przybyla, Daniel;Nubbemeyer, Udo [European Journal of Organic Chemistry,2017,vol. 2017,# 3,p. 695 - 703]