4-FLUOROPHENYLUREA synthesis
- Product Name:4-FLUOROPHENYLUREA
- CAS Number:659-30-3
- Molecular formula:C7H7FN2O
- Molecular Weight:154.14
917-61-3
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$14.30/5g
371-40-4
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$5.00/5 g
659-30-3
68 suppliers
$33.39/250mg
Yield: 80.6%
Reaction Conditions:
with acetic acid in water at 50; for 2 h;
Steps:
4 General procedure for preparation of ureas (23a-m)
General procedure: To a solution of substituted aniline (0.1 mol) dissolved in 48 mL glacial acetic acid and 96 mL H2O, sodium cyanate (13 g, 0.2 mol) in warm water (90 mL) was added with continuous stirring. The mixture was warmed to 50 C for 2 h and then cooled in ice, The crude solid, thus obtained was filtered, dried, and recrystallized with boiling water.
References:
Liao, Weike;Hu, Gang;Guo, Zhuang;Sun, Deyu;Zhang, Lixia;Bu, Yanxin;Li, Yingxiu;Liu, Yajing;Gong, Ping [Bioorganic and Medicinal Chemistry,2015,vol. 23,# 15,p. 4410 - 4422]
1195-45-5
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$6.00/1g
659-30-3
68 suppliers
$33.39/250mg
153885-60-0
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inquiry
659-30-3
68 suppliers
$33.39/250mg
352-33-0
205 suppliers
$9.00/1g
659-30-3
68 suppliers
$33.39/250mg