Aminopyrazine synthesis
- Product Name:Aminopyrazine
- CAS Number:5049-61-6
- Molecular formula:C4H5N3
- Molecular Weight:95.1
19847-12-2
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$6.00/5g
5049-61-6
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$8.00/10g
Yield:5049-61-6 82.6%
Reaction Conditions:
with sodium hypochlorite;sodium hydroxide at 20 - 60; for 5 h;
Steps:
1 Example 1,Preparation of 2-amino-pyrazine
A 500ml three-neck flask, was added at a concentration of 20% sodium hydroxide (30g) solution, and sodium hypochlorite solution (100ml), was added 2-cyano-pyrazine (21g, 0.2mol) at room temperature, the reaction was stirred for 1h. Then for 4h at 50 ~ 60 , with dichloromethane (4 × 200ml) was extracted, dried over anhydrous sodium sulfate, filtered, and concentrated under reduced pressure to give a white solid 15.7g, yield 82.6%.
References:
Hubei University of Technology;Liu, Mingxing;Jiang, Weidong;Wang, Wanxia CN105622526, 2016, A Location in patent:Paragraph 0020; 0021; 0022
32111-21-0
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$7.00/1g
5049-61-6
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$8.00/10g
94777-52-3
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$45.00/25mg
5049-61-6
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$8.00/10g
14508-49-7
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$14.00/25g
5049-61-6
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$8.00/10g
4949-13-7
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$20.00/1g
5049-61-6
444 suppliers
$8.00/10g