BETA-CHLOROLACTIC ACID synthesis
- Product Name:BETA-CHLOROLACTIC ACID
- CAS Number:1713-85-5
- Molecular formula:C3H5ClO3
- Molecular Weight:124.52
106-89-8
771 suppliers
$9.00/10 g
1713-85-5
58 suppliers
$65.00/500mg
Yield:1713-85-5 52%
Reaction Conditions:
with nitric acid at 100; for 12.5 h;Cooling with ice;
Steps:
3.1 Preparation of 3-chloro-2-hydroxypropionic acid
10.0 g of epichlorohydrin was placed in a 250 ml round bottom flask, and iceStirring in a bath, 30 ml of concentrated nitric acid (concentration 65-68%) by dropwise dropwise over about 30 minutes. Remove the ice bath and heat it100 ° C for 12 hours. Add 7 grams of sodium bicarbonate, 50 ml of anhydrous ether extraction four times. The organic phase was dried with anhydrous magnesium sulfateDried, filtered, the filtrate was concentrated in addition to the solvent and recrystallized from trichloromethane to give white crystals of 3-chloro-2-hydroxypropionic acid, yield52%.
References:
China University Of Geoscienceswuhan;ZHANG, Xiaojin;DAI, Yu CN106554342, 2017, A Location in patent:Paragraph 0012-0014
96-24-2
308 suppliers
$11.00/5g
1713-85-5
58 suppliers
$65.00/500mg
473-81-4
62 suppliers
$17.00/1g
1713-85-5
58 suppliers
$65.00/500mg
503-11-7
44 suppliers
$85.00/10mg
1713-85-5
58 suppliers
$65.00/500mg
1713-83-3
3 suppliers
inquiry
1713-85-5
58 suppliers
$65.00/500mg