ETHYL 2-NAPHTHYLACETATE synthesis
- Product Name:ETHYL 2-NAPHTHYLACETATE
- CAS Number:2876-70-2
- Molecular formula:C14H14O2
- Molecular Weight:214.26
581-96-4
231 suppliers
$6.00/5g
2876-70-2
32 suppliers
$212.00/1g
Yield:2876-70-2 286.33 grams (99%)
Reaction Conditions:
in ethanol;ethyl acetate;
Steps:
1 Ethyl 2-(2-Naphthyl)acetate
Preparation 1 Ethyl 2-(2-Naphthyl)acetate A steady stream of anhydrous hydrochloric acid was bubbled subsurface into a solution of 2-naphthylacetic acid (251.38 grams, 1.35 mol) dissolved in ethanol (1760 mL) over a period of 10 minutes. The resulting solution was stirred at ambient temperature until complete as determined by hplc (2 hours). The reaction mixture was concentrated to dryness. The resulting oil was dissolved in ethyl acetate (200 mL) and filtered through silica gel (300 grams) eluding the product with ethyl acetate (1400 mL). The filtrate was concentrated to give 286.33 grams (99%) of ethyl 2-(2-naphthyl)acetate as a colorless oil. MS (FIA) m/z 215.3 [(M+H)+]. 1H nmr (DMSO-d6): δ1.15-1.24 (t, 3H), 3.81-3.86 (d, 2H), 4.07-4.15 (q, 2H), 7.41-7.55 (m, 3H), 7.80-7.92 (m, 4H).
References:
US6329342,2001,B1
64-17-5
757 suppliers
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201230-82-2
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91-57-6
260 suppliers
$13.00/5g
2876-70-2
32 suppliers
$212.00/1g
64-17-5
757 suppliers
$10.00/50g
939-26-4
311 suppliers
$5.00/1g
199620-15-0
0 suppliers
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2876-70-2
32 suppliers
$212.00/1g