Glycidyl Palmitate synthesis
- Product Name:Glycidyl Palmitate
- CAS Number:7501-44-2
- Molecular formula:C19H36O3
- Molecular Weight:312.49
57-10-3
581 suppliers
$5.00/250mg
106-89-8
769 suppliers
$9.00/10 g
7501-44-2
35 suppliers
$250.00/10x1ml
Yield:7501-44-2 63.65%
Reaction Conditions:
with tetrabutylammomium bromide;sodium hydroxide in Petroleum ether at 50; for 5 h;Inert atmosphere;
Steps:
1.A A.
As shown in reaction 1a below, glycidyl chloride (832.68 mg, 9.0 mmol, 1.8eq.), R1-OH (1 eq., R1=palmitoyl), NaOH (1.8 eq.) and n-Bu4NBr (0.05 eq.) as a catalyst were added to 1.5 ml of PE (petroleum ether) in a nitrogen atmosphere (N2-purge). And, the temperature was raised to 50° C. and it was stirred for 5 hours. The reaction solution was diluted with 30 ml of PE and then filtered. The organic layer was dehydrated with Na2SO4, and filtered, and then concentrated. The concentrate was purified with a flash column (PE:EA (ethyl acetate)=50:1) to obtain the target compound A (R1=palmitoyl, yield=63.65%).
References:
ENZYCHEM LIFESCIENCES CORPORATION;SOHN, Ki Young;KIM, Jae Wha;YOON, Sun Young;YOO, Chang Hyun;JEONG, Jin Seon US2021/2197, 2021, A1 Location in patent:Paragraph 0040
556-52-5
280 suppliers
$17.67/1gm:
112-67-4
270 suppliers
$10.00/5mL
7501-44-2
35 suppliers
$250.00/10x1ml
556-52-5
280 suppliers
$17.67/1gm:
57-10-3
581 suppliers
$5.00/250mg
7501-44-2
35 suppliers
$250.00/10x1ml
556-52-5
280 suppliers
$17.67/1gm:
112-67-4
270 suppliers
$10.00/5mL
7501-44-2
35 suppliers
$250.00/10x1ml
30557-04-1
27 suppliers
$145.00/25mg
408-35-5
190 suppliers
$7.00/1g
106-89-8
769 suppliers
$9.00/10 g
7501-44-2
35 suppliers
$250.00/10x1ml