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ChemicalBook CAS DataBase List Lactose
63-42-3

Lactose synthesis

2synthesis methods
There are two anhydrous forms of lactose: a-lactose and b-lactose. The temperature of crystallization influences the ratio of a- and blactose. The anhydrous forms that are commercially available may exhibit hygroscopicity at high relative humidities. Anhydrous lactose is produced by roller drying a solution of lactose above 93.5°C. The resulting product is then milled and sieved. Two anhydrous a-lactoses can be prepared using special drying techniques: one is unstable and hygroscopic; the other exhibits good compaction properties. However, these materials are not commercially available.
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Yield:-

References:

Malpress;Hytten [Biochemical Journal,1958,vol. 68,p. 708,710, 713] Kuhn;Baer;Gauhe [Chemische Berichte,1955,vol. 88,p. 1145]

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