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ChemicalBook CAS DataBase List MAY-262611
1123231-07-1

MAY-262611 synthesis

1synthesis methods
488816-96-2 Synthesis
2-chloro-4-(2-naphthyl)pyrimidine

488816-96-2
16 suppliers
$336.00/1 g

7144-05-0 Synthesis
4-(Aminomethyl)piperidine

7144-05-0
213 suppliers
$6.00/1g

-

Yield: 70%

Reaction Conditions:

with N-ethyl-N,N-diisopropylamine in dimethyl sulfoxide at 80; for 2 h;

References:

Pelletier, Jeffrey C.;Lundquist IV, Joseph T.;Gilbert, Adam M.;Alon, Nipa;Bex, Frederick J.;Bhat, Bheem M.;Bursavich, Mattew G.;Coleburn, Valerie E.;Felix, Luciana A.;Green, Daniel M.;Green, Paula;Hauze, Diane B.;Kharode, Yogendra P.;Lam, Ho-Sun;Lockhead, Susan R.;Magolda, Ronald L.;Matteo, Jeanne J.;Mehlmann, John F.;Milligan, Colleen;Murrills, Richard J.;Pirrello, Jennifer;Selim, Sally;Sharp, Michael C.;Unwalla, Ray J.;Vera, Matthew D.;Wrobel, Jay E.;Yaworsky, Paul;Bodine, Peter V. N. [Journal of Medicinal Chemistry,2009,vol. 52,# 22,p. 6962 - 6965] Location in patent:supporting information; experimental part

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