METHYL 5-HYDROXY-1-NAPHTHOATE synthesis
- Product Name:METHYL 5-HYDROXY-1-NAPHTHOATE
- CAS Number:91307-40-3
- Molecular formula:C12H10O3
- Molecular Weight:202.21
83-55-6
178 suppliers
$40.00/250mg
91307-40-3
62 suppliers
$12.00/100mg
Yield:-
Steps:
Multi-step reaction with 5 steps
1.1: 65 percent / aq. HCl; NaNO2; NaI / 3 h / 0 °C
2.1: NaH / tetrahydrofuran / 0.25 h
2.2: 98 percent / tetrahydrofuran / 16 h
3.1: n-BuLi / tetrahydrofuran; hexane / 0.25 h / -78 °C
3.2: 79 percent / tetrahydrofuran; hexane / 0.08 h / -78 °C
4.1: 93 percent / BBr3 / CH2Cl2 / 16 h / 20 °C
5.1: 66 percent / CH2Cl2; diethyl ether
References:
O'Meara, Jeff A.;Yoakim, Christiane;Bonneau, Pierre R.;B?s, Michael;Cordingley, Michael G.;Déziel, Robert;Doyon, Louise;Duan, Jianmin;Garneau, Michel;Guse, Ingrid;Landry, Serge;Malenfant, Eric;Naud, Julie;Ogilvie, William W.;Thavonekham, Bounkham;Simoneau, Bruno [Journal of Medicinal Chemistry,2005,vol. 48,# 17,p. 5580 - 5588]
61735-56-6
30 suppliers
$400.00/250mg
91307-40-3
62 suppliers
$12.00/100mg
61735-51-1
10 suppliers
inquiry
91307-40-3
62 suppliers
$12.00/100mg
51934-37-3
23 suppliers
inquiry
91307-40-3
62 suppliers
$12.00/100mg
67-56-1
782 suppliers
$9.00/25ml
2437-16-3
36 suppliers
$175.00/50mg
91307-40-3
62 suppliers
$12.00/100mg