N-(2-Hydroxyethyl)-2-pyrrolidone synthesis
- Product Name:N-(2-Hydroxyethyl)-2-pyrrolidone
- CAS Number:3445-11-2
- Molecular formula:C6H11NO2
- Molecular Weight:129.16
13865-19-5
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141-43-5
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3445-11-2
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$7.00/5g
Yield:-
Reaction Conditions:
in methanol
Steps:
7 EXAMPLE 7
EXAMPLE 7 A mixture of 1.1 g of methyl 4-oxobutyrate dissolved in 2 ml methanol, 4.05 g of 2-aminoethanol, and 0.2 g of 5% Ru/C was placed in a 70 ml glass-lined pressure reactor. The reactor was flushed and then pressurized with hydrogen to 1,000 psi, sealed and shaken in an air-oven at 100° C. for four hours. After cooling and venting of unreacted hydrogen, the mixture was filtered and analyzed by gas chromatography. The analysis disclosed complete conversion of methyl 4-oxobutyrate with formation of N-(beta-hydroxyethyl)-2-pyrrolidone as confirmed by gc-mass spectrometry.
References:
National Distillers and Chemical Corporation US4420620, 1983, A
59776-88-4
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3445-11-2
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$7.00/5g
18190-44-8
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3445-11-2
151 suppliers
$7.00/5g