P-TOLUENESULFONIC ACID 1-BUTYN-3-YL ESTER synthesis
- Product Name:P-TOLUENESULFONIC ACID 1-BUTYN-3-YL ESTER
- CAS Number:53487-52-8
- Molecular formula:C11H12O3S
- Molecular Weight:224.28
98-59-9
622 suppliers
$9.00/5g
2028-63-9
216 suppliers
$10.00/1g
53487-52-8
63 suppliers
$33.00/500mg
Yield:53487-52-8 95%
Reaction Conditions:
with potassium hydroxide
Steps:
2.a a
a 2-Tosyloxy-3-butyne To a solution of tosyl chloride (0.5 mole) and commercial 3-butyn-2-ol (0.4 mole; 40-50% aqueous solution) in ether (350 ml), potassium hydroxide (2.5 moles) is slowly added over a period of 15-30 minutes. The temperature is maintained at 0°-5° C. for the entire period and the reaction mixture is allowed to stand for 90 minutes. When the reaction is complete, the ether phase is washed and dried. Removal of the ether, in vacuo, yields crude 2-tosyloxy-3-butyne. (m.p. 49°-51° C.; yield 95%).
References:
US5436273,1995,A
98-59-9
622 suppliers
$9.00/5g
53487-52-8
63 suppliers
$33.00/500mg
107-19-7
0 suppliers
$12.00/25g
2028-63-9
216 suppliers
$10.00/1g
53487-52-8
63 suppliers
$33.00/500mg
2028-63-9
216 suppliers
$10.00/1g
53487-52-8
63 suppliers
$33.00/500mg