PICRIC ACID synthesis
- Product Name:PICRIC ACID
- CAS Number:88-89-1
- Molecular formula:C6H3N3O7
- Molecular Weight:229.1
108-95-2
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88-89-1
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Yield:88-89-1 87%
Reaction Conditions:
with nitric acid in dimethyl sulfoxide at 100; for 4 h;
Steps:
Picric Acid (2,4,6-Trinitrophenol)
Phenol (0.5 g, 5.3 mmol) was dissolved in 1 mL of DMSO in a test tube and then4 mL of 63% nitric acid (55.2 mmol) was slowly dropwise added to the solution withcooling in ice-water bath. The mixture became brown. After gentle stirring, the darkbrown reaction mixture was heated under reflux in a boiling water bath for 4 h in thehood. A deep brown gas was evolved and the color of the reaction mixture changed after 1.5-2 h heating from brown to yellow. The final reaction mixture was cooled in anice-water bath and diluted with a 4-fold volume of ice-cold water. The precipitate wasisolated by vacuum filtration, washed with ice-cold water and air dried to produce yellowcrystals, 1.059 g (87% yield), mp. 122C (lit. mp. 122.5C6). IR: 3105, 1630, 1607, 1526,1429, 1339, 1312, 1177, 1148, 1087, 941, 918, 833, 783, 727, 702 cm1. ESIMS: m/zcalculated for C6H2N3O7: 227.99; found: 227.99. Elemental analysis calculated forC6H3N3O7: C, 31.45; H, 1.32; N, 18.34. Found: C, 31.39; H, 1.67; N, 18.16
References:
Khabarov, Yuri G.;Patrakeev, Aleksandr A.;Veshnyakov, Viacheslav A.;Kosyakov, Dmitry S.;Ul'yanovskii, Nikolay V.;Garkotin, Anton Yu. [Organic Preparations and Procedures International,2017,vol. 49,# 2,p. 178 - 181]
98-80-6
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88-89-1
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5570-19-4
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88-89-1
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100-01-6
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88-89-1
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51-28-5
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88-89-1
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