(R)-(+)-4-HYDROXY-2-PYRROLIDINONE synthesis
- Product Name:(R)-(+)-4-HYDROXY-2-PYRROLIDINONE
- CAS Number:22677-21-0
- Molecular formula:C4H7NO2
- Molecular Weight:101.1
208103-39-3
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22677-21-0
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Yield:-
Reaction Conditions:
in ethanol
Steps:
R.2 Production of (R)-4-hydroxy-2-pyrrolidinone without adding a base catalyst
REFERENCE EXAMPLE 2 Production of (R)-4-hydroxy-2-pyrrolidinone without adding a base catalyst An ethanol solution (50 ml) of ethyl (R)-4-amino-3-hydroxybutyrate (4.4 g, 30 mmol) was subjected to reflux under heating for 12 hours. Ethanol was distilled off and the thus-obtained crude crystals were recrystallized from ethanol (14 ml) to obtain pale yellow crystals.
References:
Daicel Chemical Industries, Ltd. US6031113, 2000, A
![2-Pyrrolidinone, 1-[(1S)-1-phenylethyl]-4-(phenylmethoxy)-, (4R)-](/CAS/20210305/GIF/135056-42-7.gif)
135056-42-7
0 suppliers
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22677-21-0
187 suppliers
$17.00/250mg