Salicylaldoxime synthesis
- Product Name:Salicylaldoxime
- CAS Number:94-67-7
- Molecular formula:C7H7NO2
- Molecular Weight:137.14
90-02-8
94-67-7
The general procedure for the synthesis of salicylaldehyde oxime from salicylaldehyde is as follows: 30 mmol of 2-hydroxybenzaldehyde, 60 mmol of sodium bicarbonate, and 45 mmol of hydroxylamine hydrochloride were dissolved in a mixed ethanol/water solvent (50 mL of ethanol/5 mL of water) at room temperature. The reaction mixture was stirred for 2 hours, followed by removal of most of the solvent by concentration. The residue was diluted with ethyl acetate and filtered directly. The filtrate was concentrated to give a final 3.99 g (98% yield) of the colorless oily product salicylaldoxime.
90-02-8
472 suppliers
$9.00/1g
94-67-7
217 suppliers
$14.00/1g
Yield:94-67-7 98%
Reaction Conditions:
with hydroxyamino hydrochloride;anhydrous sodium carbonate in ethanol;lithium hydroxide monohydrate at 20; for 2 h;
Steps:
47.1 2-hydroxybenzaldehyde oxime
At room temperature,30 mmol of 2-hydroxybenzaldehyde, 60 mmol of sodium bicarbonate,45 mmol of hydroxylamine hydrochloride were mixed in ethanol / water (50/5 mL)The reaction mixture was stirred for two hours and concentrated to remove most of the solvent.The residue was diluted with ethyl acetate and filtered directly. The filtrate was concentrated to give 3.99 g (98%) of a colorless oil.
References:
CN103864754,2016,B Location in patent:Paragraph 0378; 0379
90-01-7
361 suppliers
$5.00/1g
94-67-7
217 suppliers
$14.00/1g
89-95-2
206 suppliers
$22.00/10g
94-67-7
217 suppliers
$14.00/1g
95-48-7
453 suppliers
$18.00/25g
94-67-7
217 suppliers
$14.00/1g