TETRAFLUOROSUCCINIC ACID synthesis
- Product Name:TETRAFLUOROSUCCINIC ACID
- CAS Number:377-38-8
- Molecular formula:C4H2F4O4
- Molecular Weight:190.05
377-93-5
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$45.00/250mg
377-38-8
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$14.30/1g
Yield:377-38-8 84.1%
Reaction Conditions:
with potassium permanganate;tetrabutylammomium bromide in water;acetone at 10 - 20; for 0.5 h;
Steps:
5 Example 5
800g potassium permanganate, 10g tetrabutylammonium bromide, 400g acetone and 1200g water were put into a 5L four-necked flask with mechanical stirring, constant pressure dropping funnel, ice water reflux device and thermometer conduit.805 g (3.81 mol) of 1,2-dichlorotetrafluorocyclobutene with a content of 92.3percent was dropped under stirring, and the internal temperature was controlled at 10-20°C.After the addition, the stirring was continued at 20° C. for 0.5 h, and 1 g of sodium thiosulfate was added to remove the purple color and the reaction was terminated.The product was filtered and distilled to obtain 1482 g of recovered solvent.The filter residue was washed twice with water (200ml×2), the distillation residue was dissolved in 600ml of water, and the 1000ml solution was combined to obtain 621g of tetrafluorosuccinic acid with a purity of 98.5percent and a yield of 84.1percent.
References:
Zhong Lan Chenguang Chemical Design Yuan Co., Ltd.;Luo Kai;Luo Shengqiao;Chen Binbin;Dou Ruoan;Hu Jun;Gan Libing;Lai Bihong CN111333497, 2020, A Location in patent:Paragraph 0045
697-11-0
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377-38-8
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$14.30/1g
87-68-3
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$10.00/1g
377-38-8
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$14.30/1g
866-16-0
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$75.00/500 mg
377-34-4
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