| Identification | Back Directory | [Name]
NSC 247030 | [CAS]
114727-43-4 | [Synonyms]
SU5201
NSC 247030
NSC247030;NSC-247030;NSC 247030
2H-Indol-2-one, 3-[(3,4-dichlorophenyl)methylene]-1,3-dihydro- | [Molecular Formula]
C15H9Cl2NO | [MOL File]
114727-43-4.mol | [Molecular Weight]
290.14 |
| Chemical Properties | Back Directory | [Melting point ]
195-197 °C | [Boiling point ]
505.7±50.0 °C(Predicted) | [density ]
1.431±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
DMF:30.0(Max Conc. mg/mL);103.4(Max Conc. mM)
DMF:PBS (pH 7.2) (1:2):0.3(Max Conc. mg/mL);1.03(Max Conc. mM)
DMSO:20.0(Max Conc. mg/mL);68.93(Max Conc. mM) | [form ]
A solid | [pka]
12.54±0.20(Predicted) | [color ]
Yellow to orange |
| Hazard Information | Back Directory | [Uses]
SU5201 is an inhibitor of interleukin-2 (IL-2) production[1]. | [IC 50]
IL-2 | [storage]
4°C, protect from light | [References]
[1] Julie M. Cherrington, et al. Methods using a combination of a 3-heteroaryl-2-indolinone and a cyclooxygenase-2 inhibitor for the treatment of neoplasia. EP1509224A1. |
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