| Identification | More | [Name]
(S)-3-Hydroxypyrrolidine hydrochloride | [CAS]
122536-94-1 | [Synonyms]
3-PYRROLIDINOL, HYDROCHLORIDE, (3S)
(S)-3-HYDROXY PYRROLIDINE HCL
(S)-3-HYDROXYPYRROLIDINE HYDROCHLORIDE
(S)-(-)-3-PYRROLIDINOL HYDROCHLORIDE
(S)-3-PYRROLIDINOL HYDROCHLORIDE
(S)-PYRROLIDIN-3-OL HCL
(S)-PYRROLIDINE-3-OL HYDROCHLORIDE
TIMTEC-BB SBB004272
S-(+)-3-PyrrolidinolHCl
(S)-3-hydroxypyrrolidine hydrochoride
(S)-pyrrolidin-3-ol hydrochloride
(S)-(+)-3-PYRROLIDINOL HYDROCHLORIDE,98% | [EINECS(EC#)]
672-315-7 | [Molecular Formula]
C4H10ClNO | [MDL Number]
MFCD00272298 | [Molecular Weight]
123.58 | [MOL File]
122536-94-1.mol |
| Chemical Properties | Back Directory | [Appearance]
almost white crystalline powder | [Melting point ]
104-107°C | [Boiling point ]
108-110℃/8mm | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
DMSO (Sparingly), Methanol (Slightly) | [form ]
Solid | [color ]
Off-White to Pale Beige | [Detection Methods]
T | [Stability:]
Hygroscopic | [InChI]
InChI=1/C4H9NO.ClH/c6-4-1-2-5-3-4;/h4-6H,1-3H2;1H/t4-;/s3 | [InChIKey]
QPMSJEFZULFYTB-NDILARRWNA-N | [SMILES]
O[C@@H]1CNCC1.Cl |&1:1,r| | [CAS DataBase Reference]
122536-94-1(CAS DataBase Reference) | [Storage Precautions]
Air sensitive;Moisture sensitive |
| Hazard Information | Back Directory | [Chemical Properties]
almost white crystalline powder | [Uses]
(S)-3-Hydroxypyrrolidine Hydrochloride is a useful intermediate for the synthesis of Asimadoline Hydrochlorine (A788250), used in the treatment of IBS, a disorder associated with pain and altered bowel function. | [References]
[1] Patent: EP2803664, 2014, A1. Location in patent: Paragraph 0153; 0154
[2] Patent: US2015/5282, 2015, A1. Location in patent: Paragraph 0224; 0225
[3] Patent: CN105646321, 2016, A. Location in patent: Paragraph 0031; 0032 |
|
|