| Identification | Back Directory | [Name]
Phenol, 2-methoxy-4-[1-[2-(1-methyl-2-pyrrolidinyl)ethyl]-4-phenyl-1H-imidazol-5-yl]- | [CAS]
1269190-98-8 | [Synonyms]
yGsy2p-IN-H23
Phenol, 2-methoxy-4-[1-[2-(1-methyl-2-pyrrolidinyl)ethyl]-4-phenyl-1H-imidazol-5-yl]- | [Molecular Formula]
C23H27N3O2 | [MDL Number]
MFCD18639203 | [MOL File]
1269190-98-8.mol | [Molecular Weight]
377.48 |
| Chemical Properties | Back Directory | [Boiling point ]
545.8±45.0 °C(Predicted) | [density ]
1.19±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
9.72±0.20(Predicted) | [color ]
Off-white to brown |
| Hazard Information | Back Directory | [Uses]
yGsy2p-IN-H23 is a potent and first-in-class inhibitor for yeast glycogen synthase 2 (yGsy2p) with an IC50 of 875 μM for human glycogen synthase 1 (hGYS1). yGsy2p-IN-H23 bounds within the uridine diphosphate glucose binding pocket of yGsy2p. yGsy2p-IN-H23 is used for the research of glycogen storage diseases (GSDs)[1]. | [storage]
Store at -20°C | [References]
[1] Buyun Tang, et al. Discovery and Development of Small-Molecule Inhibitors of Glycogen Synthase. J Med Chem. 2020 Apr 9;63(7):3538-3551. DOI:10.1021/acs.jmedchem.9b01851 |
|
| Company Name: |
MedChemExpress
|
| Tel: |
021-58955995 |
| Website: |
www.medchemexpress.com |
|