1269190-98-8
中文名稱
YGSY2P-IN-H23
英文名稱
Phenol, 2-methoxy-4-[1-[2-(1-methyl-2-pyrrolidinyl)ethyl]-4-phenyl-1H-imidazol-5-yl]-
CAS
1269190-98-8
分子式
C23H27N3O2
分子量
377.48
MOL 文件
1269190-98-8.mol
1269190-98-8 結構式
基本信息
英文別名
yGsy2p-IN-H23Phenol, 2-methoxy-4-[1-[2-(1-methyl-2-pyrrolidinyl)ethyl]-4-phenyl-1H-imidazol-5-yl]-
物理化學性質
沸點545.8±45.0 °C(Predicted)
密度1.19±0.1 g/cm3(Predicted)
儲存條件-20°C儲存
酸度系數(shù)(pKa)9.72±0.20(Predicted)
形態(tài)Solid
顏色Off-white to brown
YGSY2P-IN-H23價格(試劑級)
| 報價日期 | 產品編號 | 產品名稱 | CAS號 | 包裝 | 價格 |
| 2025/05/22 | HY-131177 | yGsy2p-IN-H23 | 1269190-98-8 | 5mg | 2000元 |
| 2025/05/22 | HY-131177 | yGsy2p-IN-H23 | 1269190-98-8 | 10mM * 1mLin DMSO | 2200元 |
| 2025/05/22 | HY-131177 | yGsy2p-IN-H23 | 1269190-98-8 | 10mg | 3500元 |
常見問題列表
生物活性
yGsy2p-IN-H23 是一種有效的酵母糖原合酶 2 (yGsy2p) 抑制劑，對人糖原合酶 1 (hGYS1) 的 IC50 為 875 μM。yGsy2p-IN-H23 結合在 yGsy2p 的尿苷二磷酸葡萄糖結合口袋內。yGsy2p-IN-H23 用于糖原儲存疾病 (GSDs) 的相關研究。靶點
IC50: 875 μM (hGYS1)
體外研究
yGsy2p-IN-H23 (compound H23) has IC 50 values against either hGYS1Δ634S8,11N or wild-type hGYS1 were 161 μM and 875 μM, respectively. yGsy2p-IN-H23 exhibits IC 50 values of 280 μM and 263 μM in the absence and presence of G6P for yGsy2p against yeast and human glycogen synthase (GS), respectively. yGsy2p-IN-H23 is not in direct competition with G6P.