| Identification | Back Directory | [Name]
exo BCN-O-PNB | [CAS]
1380006-72-3 | [Synonyms]
exo BCN-O-PNB
BCN-PNP (EXO)
exo BCN-O-PNP
exo BCN - active ester (p-NPE)
exo BCN - active ester (p-NPC)
((1R,8S,9R)-Bicyclo[6.1.0]non-4-yn-9-yl)methyl 4-nitrophenyl carbonate
rel-((1R,8S,9r)-Bicyclo[6.1.0]non-4-yn-9-yl)methyl (4-nitrophenyl) carbonate
Carbonic acid, (1α,8α,9α)-bicyclo[6.1.0]non-4-yn-9-ylmethyl 4-nitrophenyl ester | [Molecular Formula]
C17H17NO5 | [MDL Number]
MFCD23378570 | [MOL File]
1380006-72-3.mol | [Molecular Weight]
315.33 |
| Hazard Information | Back Directory | [Uses]
exo BCN-O-PNB is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. exo BCN-O-PNB is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. | [IC 50]
Alkyl/ether | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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