| Identification | More | [Name]
3-Aminobenzylamine | [CAS]
4403-70-7 | [Synonyms]
3-AMINOBENZYLAMINE
3-(AMINOMETHYL)ANILINE
ALPHA-AMINO-M-TOLUIDINE
RARECHEM AL BW 0272
m-Aminobenzylamine
3-(Aminomethyl)benzenamine
3-Aminobenzenemethanamine
m-Aminomethylaniline | [EINECS(EC#)]
412-230-2 | [Molecular Formula]
C7H10N2 | [MDL Number]
MFCD00078355 | [Molecular Weight]
122.17 | [MOL File]
4403-70-7.mol |
| Chemical Properties | Back Directory | [Appearance]
Pale brown low melting solid | [Melting point ]
41-45 °C | [Boiling point ]
134°C/4mmHg(lit.) | [density ]
1.093±0.06 g/cm3(Predicted) | [Fp ]
>110℃ | [storage temp. ]
2-8°C, protect from light | [solubility ]
soluble in Methanol | [form ]
Low Melting Solid | [pka]
9.22±0.10(Predicted) | [color ]
Pale brown | [CAS DataBase Reference]
4403-70-7(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
N,C | [Risk Statements ]
R34:Causes burns.
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
R22:Harmful if swallowed. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S22:Do not breathe dust . | [RIDADR ]
3259 | [WGK Germany ]
3 | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29215900 |
| Hazard Information | Back Directory | [Chemical Properties]
Pale brown low melting solid | [Synthesis Reference(s)]
Synthetic Communications, 25, p. 863, 1995 DOI: 10.1080/00397919508013422 | [Synthesis]
The general procedure for the synthesis of 3-aminobenzylamine from the compound (CAS:3717-30-4) is as follows:
Example 18: 16.6 g (0.1 mol) of m-nitrobenzaldehyde oxime made in Example 15, 9.5 g (0.05 mol) of p-toluenesulfonic acid, 0.5 g of 5% Pt-C catalyst and 75 mL of dioxane were added to a sealed glass vessel. Vigorous stirring was carried out under hydrogen-filled conditions. The reaction was continued at 30°C to 40°C for 8 hours. Upon completion of the reaction, the mixture was filtered to remove the catalyst, followed by the addition of 35 g (0.3 mol) of 35% aqueous sodium hydroxide. After stirring, the mixture was allowed to stand until layered. The lower layer was separated and discarded and the upper layer was distilled. Finally 8.9 g of m-aminobenzylamine was obtained in 72.9% yield and 99.3% purity by gas chromatography. | [References]
[1] Patent: US4751328, 1988, A
[2] Patent: US4751328, 1988, A |
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