| Identification | More | [Name]
CYCLOPENTYL PHENYL KETONE | [CAS]
5422-88-8 | [Synonyms]
BENZOYLCYCLOPENTANE
CYCLOPENTYL PHENYL KETONE
CYCLOPENTYLPHENYLMETHANONE
TIMTEC-BB SBB007885
Cyclopentanylphenylmethanone
cyclopentylphenyl-methanon
Ketone, cyclopentyl phenyl
Cyclopentylphenylketone,96% | [EINECS(EC#)]
226-548-2 | [Molecular Formula]
C12H14O | [MDL Number]
MFCD00001378 | [Molecular Weight]
174.24 | [MOL File]
5422-88-8.mol |
| Chemical Properties | Back Directory | [Boiling point ]
136-140°C 16mm | [density ]
1,036 g/cm3 | [refractive index ]
1.5440 | [Fp ]
>110°C | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Chloroform, Methanol (Slightly) | [form ]
Oil | [color ]
Pale Yellow | [Specific Gravity]
1.04 | [BRN ]
2045903 | [InChI]
InChI=1S/C12H14O/c13-12(11-8-4-5-9-11)10-6-2-1-3-7-10/h1-3,6-7,11H,4-5,8-9H2 | [InChIKey]
VYDIMQRLNMMJBW-UHFFFAOYSA-N | [SMILES]
C(C1CCCC1)(C1=CC=CC=C1)=O | [CAS DataBase Reference]
5422-88-8(CAS DataBase Reference) | [EPA Substance Registry System]
Methanone, cyclopentylphenyl- (5422-88-8) |
| Safety Data | Back Directory | [Safety Statements ]
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
S24/25:Avoid contact with skin and eyes . | [TSCA ]
Yes | [HS Code ]
2914.39.9000 |
| Hazard Information | Back Directory | [Description]
Phenyl cyclopentyl ketone (Item No. 31036) is an analytical reference standard categorized as a precursor in the synthesis of ketamine (Item Nos. 19389 | 11630). This product is intended for research and forensic applications. | [Uses]
Phenylcyclopentyl ketone is the key intermediate of synthetic hydrochloric acid amyl ethyl quin ether. | [Synthesis]
In 100ml round-bottomed flask, by 2-cyclopenta ethyl benzoylacetate (10.6g, 43.05mmol, 1.0eq), NaOH (2.6g, 64.5mmol) and Na2CO3(4.5g, 43mmol), is suspended in 50.0mLH2In O, it is warmed up to 80 DEG C and reacts 3 hours, obtain product phenylcyclopentyl ketone.Purify: reactant liquor is cooled to room temperature, extract 3 times with ethyl acetate 20mL；Organic phase saturated sodium-chloride washs, and merges organic phase and uses anhydrous MgSO4Being dried, then remove solvent under reduced pressure, obtain thick product, column chromatography purifies, and eluant, eluent is ethyl acetate: petroleum ether (1:10), obtains 6.54g target product, yield 87.2%. |
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