| Identification | More | [Name]
5-[(2-Hydroxyethyl)amino]-o-cresol | [CAS]
55302-96-0 | [Synonyms]
2-METHYL-5-HYDROXYETHYLAMINOPHENOL
2-METHYL-5-N-(BETA-HYDROXYETHYL)AMINO PHENOL
2-Methyl-5-N-hydroxyethylamino phenol
5[(2-HYDROXYETHYL)AMINO]-2-METHYL PHENOL
5-[(2-HYDROXYETHYL)AMINO]-O-CRESOL
1-methyl-2-hydroxy-4-(beta-hydroxyethyl)aminobenzene
2-hydroxy-4-(beta-hydroxyethyl)aminotoluene
5-((2-hydroxyethyl)amino)-2-methyl-pheno
6-methyl-3-beta-hydroxyethylaminophenol
5-(N-hydroxyethyl)-amino ortho methyl phenol
N-HydroxyethylAmino-O-Cresol
Phenol, 5-(2-hydroxyethyl)amino-2-methyl-
2-Methyl-5-(2-hydroxyethylamino)phenol | [EINECS(EC#)]
259-583-7 | [Molecular Formula]
C9H13NO2 | [MDL Number]
MFCD01707346 | [Molecular Weight]
167.21 | [MOL File]
55302-96-0.mol |
| Chemical Properties | Back Directory | [Appearance]
Light brown powder | [Melting point ]
90-92℃ | [Boiling point ]
366.0±32.0 °C(Predicted) | [density ]
1?+-.0.06 g/cm3(Predicted) | [vapor pressure ]
0.004Pa at 20℃ | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
10.28±0.10(Predicted) | [color ]
Light Beige | [Water Solubility ]
37g/L at 20℃ | [LogP]
0.772 at 23℃ | [CAS DataBase Reference]
55302-96-0(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Chemical Properties]
Light brown powder | [Flammability and Explosibility]
Notclassified | [Synthesis]
In a 250 mL four-necked flask fitted with a thermometer and stirrer, 12.3 g (0.1 mol) of 5-amino-2-methylphenol was dissolved in 80 mL of diethylene glycol dimethyl ether and heated to 150 °C. Under slow stirring in a cold trap, 4.4 g (0.1 mol) of ethylene oxide was dissolved in 10 mL of diethylene glycol dimethyl ether and 0.3 g of NaY molecular sieve catalyst was added to a four-necked flask, followed by dropwise addition of the mixture. After the dropwise addition process lasted for 0.5 hr, the reaction was continued for 3 hr. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure, dried and the residue was cooled to give 16.6 g of 5-(2-hydroxyethyl)amino-o-cresol crude product. The crude product was dissolved in 100 mL of methanol-water mixed solvent and recrystallized to give 15.7 g of refined 5-(2-hydroxyethyl)amino-o-cresol in 94.1% yield and 99.52% purity. | [References]
[1] Patent: CN106588678, 2017, A. Location in patent: Paragraph 0025; 0026; 0028; 0030; 0031; 0032; 0034 |
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