| Identification | More | [Name]
2,2'-Bipyridine-4,4'-dicarboxylic acid | [CAS]
6813-38-3 | [Synonyms]
2,2'-BIISONICOTINIC ACID
2,2'-BIPYRIDINE-4,4'-DICARBOXYLIC ACID
2,2'-BIPYRIDYL-4,4'-DICARBOXYLIC ACID
2,2'-DIPYRIDYL-4,4'-DICARBOXYLIC ACID
4,4'-DICARBOXY-2,2'-BIPYRIDINE
RARECHEM AL BE 0816
2,2'-BIPYRIDINE-4,4'-DICARBOXYLIC ACID,98 %
2,2'-BIPYRIDINE-4,4'-DICARBOXYLIC ACID, TECH., 90%
2,2'-Bipyridyl-4,4'-dicarboxyl
4,4'-Dicarboxy-2,2'-bipyridine,98%
4,4'-dicarboxylic acid-2,2'-dipyridine
4,4-DICARBOXY-2,2-DIPIPIDYL
2,2'-Bi(4-pyridinecarboxylic acid)
2,2'-Bi[4-pyridinecarboxylic acid]
dcbpy | [EINECS(EC#)]
626-224-4 | [Molecular Formula]
C12H8N2O4 | [MDL Number]
MFCD00015430 | [Molecular Weight]
244.2 | [MOL File]
6813-38-3.mol |
| Chemical Properties | Back Directory | [Appearance]
white to white-grey powder | [Melting point ]
>310°C | [Boiling point ]
387.12°C (rough estimate) | [density ]
1.3468 (rough estimate) | [refractive index ]
1.6360 (estimate) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [form ]
Powder | [pka]
1.67±0.10(Predicted) | [color ]
White to white-gray | [Water Solubility ]
insoluble | [BRN ]
212894 | [InChI]
InChI=1S/C12H8N2O4/c15-11(16)7-1-3-13-9(5-7)10-6-8(12(17)18)2-4-14-10/h1-6H,(H,15,16)(H,17,18) | [InChIKey]
FXPLCAKVOYHAJA-UHFFFAOYSA-N | [SMILES]
C1(C2=NC=CC(C(O)=O)=C2)=NC=CC(C(O)=O)=C1 | [CAS DataBase Reference]
6813-38-3(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [HazardClass ]
IRRITANT | [HS Code ]
29333990 |
| Hazard Information | Back Directory | [Chemical Properties]
white to white-grey powder | [Uses]
2,2'-Bipyridine-4,4'-dicarboxylic acid can be used as an organic chemical synthesis intermediate
| [Synthesis]
General procedure for the synthesis of 2,2'-bipyridine-4,4'-dicarboxylic acid from 4,4'-dimethyl-2,2'-bipyridine: 1.0 g (5.4 mmol) of 4,4'-dimethyl-2,2'-bipyridine was added to a reaction flask, and 18 mL of concentrated sulfuric acid was added slowly dropwise with stirring. This process was accompanied by a large amount of exothermic heat, and after the solution was cooled to room temperature, 3.3 g (11.3 mmol) of potassium dichromate was added, and the solution then changed to a dark green color. Subsequently, the reaction mixture was stirred at 65°C for 6 hours. Upon completion of the reaction, it was cooled to room temperature and the reaction was poured into 1000 mL of water, which immediately produced a large white flocculent precipitate. The precipitate was collected by filtration and washed sequentially with water and methanol until the filtrate was clarified. Finally, the resulting white solid was dried under vacuum at 60 °C for 18 h to obtain the target product in 98% yield. | [References]
[1] Chemical Communications, 2010, vol. 46, # 13, p. 2197 - 2199
[2] Transition Metal Chemistry, 2011, vol. 36, # 8, p. 897 - 900
[3] Patent: CN107417737, 2017, A. Location in patent: Paragraph 0051-0054
[4] Helvetica Chimica Acta, 2018, vol. 101, # 5,
[5] Chemical Communications, 2006, # 1, p. 85 - 87 |
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