| Identification | More | [Name]
Butyl hydroxyacetate | [CAS]
7397-62-8 | [Synonyms]
BUTYL GLYCOLATE
BUTYL HYDROXYACETATE
N-BUTYL GLYCOLATE
Acetic acid, hydroxy-, butyl ester
Aceticacid,hydroxy-,butylester
hydroxy-aceticacibutylester
hydroxyaceticacidbutylester
butyl glycollate
Glycol acid-n-butylester
Glycolic acid, n-butyl ester
Hydroxyacetic acid, n-butyl ester
n-Butyl hydroxyacetate
Glycolsure-n-butylester
Buthyl Glycolate | [EINECS(EC#)]
230-991-7 | [Molecular Formula]
C6H12O3 | [MDL Number]
MFCD00042732 | [Molecular Weight]
132.16 | [MOL File]
7397-62-8.mol |
| Chemical Properties | Back Directory | [Boiling point ]
187-190 °C(lit.)
| [density ]
1.019 g/mL at 20 °C(lit.)
| [vapor pressure ]
1.3hPa at 20℃ | [refractive index ]
n20/D 1.427
| [Fp ]
74 °C | [storage temp. ]
Sealed in dry,2-8°C | [pka]
12.99±0.10(Predicted) | [Appearance]
Colorless to light yellow Liquid | [Water Solubility ]
46g/L at 20℃ | [BRN ]
1749477 | [InChI]
InChI=1S/C6H12O3/c1-2-3-4-9-6(8)5-7/h7H,2-5H2,1H3 | [InChIKey]
VFGRALUHHHDIQI-UHFFFAOYSA-N | [SMILES]
C(OCCCC)(=O)CO | [LogP]
0.38 at 25℃ | [CAS DataBase Reference]
7397-62-8(CAS DataBase Reference) | [NIST Chemistry Reference]
Butyl glycolate(7397-62-8) | [EPA Substance Registry System]
7397-62-8(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
63-41 | [Safety Statements ]
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
S24/25:Avoid contact with skin and eyes . | [RIDADR ]
NA 1993 / PGIII | [WGK Germany ]
1
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| Hazard Information | Back Directory | [Chemical Properties]
Colorless Transparent Liquid | [Uses]
Butyl glycolate may be used in the preparation of N-(α-hydroxyacetyl)-(S)-isoleucine. | [Production Methods]
n-Butyl glycolate is produced
by treatment of sodium chloroacetate with nbutyl alcohol at 125 – 160℃, followed by vacuum distillation. | [General Description]
Butyl glycolate is a glycolic acid derivative. | [Purification Methods]
Dissolve in CHCl3 (EtOH-free), wash with 5% KHCO3 until effervescence ceases (if free acid is present), dry over CaCl2, filter, evaporate and distil through a short column. [B.hme & Opfer Z Anal Chem 139 255 1953, Filachione et al. J Am Chem Soc 73 5265 1951, Beilstein 3 IV 589.] | [References]
[1] Patent: CN105130801, 2017, B. Location in patent: Paragraph 0031; 0032; 0033; 0034; 0035; 0036; 0037-0049
[2] Journal of the Chemical Society of Pakistan, 2014, vol. 36, # 6, p. 1109 - 1113
[3] Journal of the American Pharmaceutical Association (1912-1977), 1941, vol. 30, p. 133
[4] Chem.Abstr., 1941, p. 6235
[5] Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 16, p. 259 |
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