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2457-80-9

中文名稱(chēng) 5-脫氧-5-甲硫腺苷
英文名稱(chēng) 5'-DEOXY-5'-METHYLTHIOADENOSINE
CAS 2457-80-9
分子式 C11H15N5O3S
分子量 297.33
MOL 文件 2457-80-9.mol
更新日期 2025/07/22 16:38:11
2457-80-9 結(jié)構(gòu)式 2457-80-9 結(jié)構(gòu)式

基本信息

中文別名
甲硫腺苷
甲硫腺苷對(duì)照品
5'-甲硫腺苷
5′-脫氧-5′-腺苷
5-脫氧-5-甲硫腺苷
5ˊ-脫氧-5ˊ-甲硫基腺苷
5'-脫氧-5'-硫代甲基酰苷
5'-S-甲基-5'-硫代腺苷
甲硫腺苷:5-脫氧-5-甲硫腺苷
5-脫氧-5-甲硫腺苷 (5'-脫氧-5'-硫代甲基酰苷、5ˊ-脫氧-5ˊ-甲硫基腺苷)
英文別名
MTA
MESADO
SKL060
2457-80-9
NSC 335422
vitaminl(sub2)
1-(6-AMino-9H-purin
Methylthioadenosine
5’-methylthioadenosine
Adenylthiomethylpentose
所屬類(lèi)別
生物化工:脫氧核苷酸及其類(lèi)似物

物理化學(xué)性質(zhì)

熔點(diǎn)210-213 °C (dec.)
沸點(diǎn)642.7±65.0 °C(Predicted)
密度1.85±0.1 g/cm3(Predicted)
儲(chǔ)存條件−20°C
溶解度DMF(少量)、DMSO(少量)、甲醇(少量)
酸度系數(shù)(pKa)13.10±0.70(Predicted)
形態(tài)白色固體
顏色白色至灰白色
生物來(lái)源synthetic (organic)
BRN42420

安全數(shù)據(jù)

危險(xiǎn)性符號(hào)(GHS)GHS hazard pictograms
GHS07
警示詞警告
危險(xiǎn)性描述H315-H319
安全說(shuō)明22-24/25
WGK Germany3
RTECS號(hào)AU7410000

常見(jiàn)問(wèn)題列表

簡(jiǎn)介
5-脫氧-5-甲硫腺苷是一種C-5' 的羥基被甲硫基(甲硫基)取代的腺苷,可用作抑制劑。
生物活性
5'-Methylthioadenosine 是由 S-腺苷酸產(chǎn)生的,有強(qiáng)效的抑制作用。
靶點(diǎn)

Human Endogenous Metabolite

體外研究

5'-Methylthioadenosine (MTA) can affect cellular processes in many ways. 5'-Methylthioadenosine has been shown to influence numerous critical responses of the cell including regulation of gene expression, proliferation, differentiation and apoptosis. Although most of these responses have been observed at the pharmacological level, their specificity makes it tempting to speculate that endogenous 5'-Methylthioadenosine could play a regulatory role in the cell. Finally, observations carried out in models of liver damage and cancer demonstrate a therapeutic potential for 5'-Methylthioadenosine that deserves further consideration [1] .

5-脫氧-5-甲硫腺苷價(jià)格(試劑級(jí))
報(bào)價(jià)日期產(chǎn)品編號(hào)產(chǎn)品名稱(chēng)CAS號(hào)包裝價(jià)格
2025/05/22HY-169385-脫氧-5-甲硫腺苷
5'-Methylthioadenosine
2457-80-925mg500元
2025/05/22HY-169385-脫氧-5-甲硫腺苷
5'-Methylthioadenosine
2457-80-910mM * 1mLin DMSO550元
2025/05/22HY-169385-脫氧-5-甲硫腺苷
5'-Methylthioadenosine
2457-80-950 mg850元
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