26348-70-9
26348-70-9 結(jié)構(gòu)式
基本信息
L-賴氨酸甲酯二鹽酸鹽
H-LYS-OME 2HCL
L-LYSINE METHYL ESTER DIHCL
L-LYSINE METHYL ESTER DIHYDROCHLORIDE
L-LYSINE METHYL ESTER DIHYDROCHLORIDE SALT
L-LYSINE METHYL ESTER HYDROCHLORIDE
LYSINE-OME 2 HCL
METHYL (S)-2,6-DIAMINOHEXANOIC ACID DIHYDROCHLORIDE
methyl L-lysinate dihydrochloride
L-Lysine Methyl Ester 2HCl
L-LYSINE METHYL ESTER DIHYDROCHLORIDE 99%
L-Lysinemethylesterdihydrochloride,99%
Methyl L-Lysine Dihydrochloride
(s)-2,6-diaminohexanoic acid methyl ester dihydrochloride
LYS.OME.2HCL
H-L-Lys-OMe*2HCl
L-Lysine methyl·dihydrochloride
物理化學(xué)性質(zhì)
安全數(shù)據(jù)
制備方法
67-56-1
657-27-2
13515-95-2
向圓底燒瓶中加入L-賴氨酸鹽酸鹽（2,5.00g，27.4mmol，1.0當(dāng)量）和甲醇（30mL，0.9M）。將懸浮液加熱至回流狀態(tài)直至固體完全溶解。緩慢滴加亞硫酰氯（2.59mL，35.6mmol，1.3當(dāng)量），控制滴加時(shí)間在15分鐘內(nèi)。保持反應(yīng)體系在回流條件下反應(yīng)17小時(shí)。反應(yīng)完成后，通過蒸餾移除大部分揮發(fā)性物質(zhì)（約25mL），隨后在減壓條件下與甲苯共沸除去剩余揮發(fā)物，得到純的賴氨酸甲酯二鹽酸鹽（3，定量收率，白色固體），該產(chǎn)物無需進(jìn)一步純化即可直接用于下一步反應(yīng)。經(jīng)分析，所得化合物的物理和化學(xué)性質(zhì)與文獻(xiàn)報(bào)道數(shù)據(jù)一致。
參考文獻(xiàn)：
[1] Tetrahedron Letters, 2016, vol. 57, # 4, p. 502 - 504
[2] Journal of Medicinal Chemistry, 2002, vol. 45, # 17, p. 3669 - 3683
[3] Heterocycles, 2017, vol. 94, # 5, p. 964 - 978
[4] Journal of Polymer Science, Part A: Polymer Chemistry, 2015, vol. 53, # 17, p. 2036 - 2049
[5] Molecules, 2016, vol. 21, # 1,
| 報(bào)價(jià)日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價(jià)格 |
| 2025/05/22 | A18157 | L-賴氨酸甲酯二鹽酸鹽, 99% L-Lysine methyl ester dihydrochloride, 99% | 26348-70-9 | 25g | 641元 |
| 2025/05/22 | A18157 | L-賴氨酸甲酯二鹽酸鹽, 99% L-Lysine methyl ester dihydrochloride, 99% | 26348-70-9 | 100g | 1774元 |
| 2025/05/22 | A18157 | L-賴氨酸甲酯二鹽酸鹽, 99% L-Lysine methyl ester dihydrochloride, 99% | 26348-70-9 | 500g | 6438元 |