42882-31-5
42882-31-5 結(jié)構(gòu)式
基本信息
1-(1-萘基)氨基乙烷
(±)-1-萘基乙氨,98%
1-(1-NAPHTHYL)ETHYLAMINE
1-NAPHTHALEN-1-YL-ETHYLAMINE
1-NAPHTHYLETHYLAMINE
(+/-)-alpha-Methyl-1-naphthalenemethylamine
DL-1-(1-NAPHTHYL)ETHYLAMINE
DL-ALPHA-(1-AMINOETHYL)NAPHTHALENE
DL-ALPHA-(1-NAPHTHYL)ETHYLAMINE
(+)-1-(1-Naphtyl)ethylamine
(+/-)-1-naphthalenemethanamin
(R)-(+)-1-(1-Nphthyl)ethylamne
Naphthylethylamine
(+/-)-1-(1-NPHTHYL)ETHYLAMNE
(±)-1-(1-Naphthyl)ethylamine,98%
1-Naphthaleneethylamine
1-Naphthalenemethanamine, .alpha.-methyl-
(n)-1-(1-naphthyl)ethylamine
(+/-)1-(1-Naphthyl)ethylamine
(+/-)-alpha-Methyl-1-naphthalenemethylamine
(±)-α-Methyl-1-naphthalenemethylamine, (±)-1-(1-Naphthyl)ethylamine
物理化學(xué)性質(zhì)
安全數(shù)據(jù)
制備方法
941-98-0
42882-31-5
以1-萘乙酮為原料合成1-萘乙胺的一般步驟：將相應(yīng)的酮（10mmol，具體為1.14g的1a，0.98g的1b，1.48g的1c，1.46g的1d，1.46g的1e，1.32g的1f，1.20g的1g，1.70g的1h，1.70g的1i）與羥胺鹽酸鹽（15mmol，1.04g）、甲酸銨（60mmol，3.78g）和鋅粉（30mmol，1.96g）在甲醇（30mL）中混合，于回流條件下攪拌反應(yīng)。反應(yīng)完成后，將反應(yīng)混合物通過Celite過濾。濾液經(jīng)真空旋轉(zhuǎn)蒸發(fā)除去溶劑。殘余物用濃鹽酸處理，隨后加入4mL HCl溶液和30mL水，用乙醚（2×20mL）萃取以去除有機(jī)雜質(zhì)。水相用氨水調(diào)節(jié)至pH=10，再用二氯甲烷（4×25mL）萃取。合并有機(jī)相，用飽和食鹽水洗滌，無水硫酸鈉干燥，最后真空除去溶劑得到目標(biāo)產(chǎn)物1-萘乙胺。
參考文獻(xiàn)：
[1] Tetrahedron Letters, 2011, vol. 52, # 12, p. 1310 - 1312
[2] Journal of Medicinal Chemistry, 2006, vol. 49, # 21, p. 6197 - 6208
[3] Patent: WO2008/58235, 2008, A2. Location in patent: Page/Page column 23-24
[4] Synthetic Communications, 2011, vol. 41, # 3, p. 341 - 346
[5] Molecules, 2014, vol. 19, # 12, p. 21386 - 21397
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2025/05/22 | L09342 | (±)-1-萘基乙氨,98% (±)-1-(1-Naphthyl)ethylamine, 98% | 42882-31-5 | 5g | 470元 |
| 2025/05/22 | L09342 | (±)-1-萘基乙氨,98% (±)-1-(1-Naphthyl)ethylamine, 98% | 42882-31-5 | 25g | 2111元 |
| 2025/05/22 | 45057 | (±)-1-萘基乙氨 1-(1-Naphthyl)ethylamine, 98%, Thermo Scientific Chemicals | 42882-31-5 | 5g | 329元 |