3-[4-[[[(3-Methylphenyl)amino]carbonyl]amino]-1H-pyrazol-1-yl]-N-(3,4,5-trimethoxyphenyl)-benzamide
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3-[4-[[[(3-Methylphenyl)amino]carbonyl]amino]-1H-pyrazol-1-yl]-N-(3,4,5-trimethoxyphenyl)-benzamide Eigenschaften
- Siedepunkt:
- 557.7±50.0 °C(Predicted)
- Dichte
- 1.27±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- L?slichkeit
- DMSO: ≥20mg/mL
- Aggregatzustand
- powder
- pka
- 11.51±0.70(Predicted)
- Farbe
- light brown to brown
- Stabilit?t:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Sicherheit
WGK Germany | 3 | ||
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HS Code | 2933399990 |
3-[4-[[[(3-Methylphenyl)amino]carbonyl]amino]-1H-pyrazol-1-yl]-N-(3,4,5-trimethoxyphenyl)-benzamide Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
SR 3576 is a JNK-3 selective inhibitor.Allgemeine Beschreibung
A cell-permeable pyrazolourea compound that acts as a potent, ATP binding pocket-targeting, and JNK3-selective inhibitor (IC50 = 7 nM), inhibiting JNK1 only at much higher concentrations (IC50 = 170 nM) and exhibiting little activity against p38 even at concentrations as high as 20 μM. Shown to inhibit streptozotocin- (Cat. No. 572201) induced c-jun phosphorylation in INS-1 rat β-pancreatic cells (IC50 = 1.3 μM).Biochem/physiol Actions
SR-3576 is a small molecule inhibitor belonging to aminopyrazole class that selectively inhibits JNK3 with >2800 fold selectively over p38.13-[4-[[[(3-Methylphenyl)amino]carbonyl]amino]-1H-pyrazol-1-yl]-N-(3,4,5-trimethoxyphenyl)-benzamide Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
3-[4-[[[(3-Methylphenyl)amino]carbonyl]amino]-1H-pyrazol-1-yl]-N-(3,4,5-trimethoxyphenyl)-benzamide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 55)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 |
marketing@targetmol.com | United States | 32376 | 58 |
Aladdin Scientific | |
tp@aladdinsci.com | United States | 52924 | 58 |
Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51395 | 80 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9803 | 58 |
Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 |
3008007409@qq.com | China | 71826 | 60 |
BOC Sciences | -- |
info@bocsci.com | USA | 0 | 65 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11218 | 58 |
Energy Chemical | 021-58432009 400-005-6266 |
marketing1@energy-chemical.com | China | 44814 | 58 |
MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 |
order@med-bio.cn | China | 8140 | 58 |
Jinan Jiuli Biotechnology Co. , Ltd. | 15865264761 |
486064515@qq.com | China | 4775 | 58 |
- 3-(5-(3-m-Tolylureido)-1H-indazol-1-yl)-N-(3,4,5-trimethoxyphenyl)benzamide
- SR-3576
- JNK3 Inhibitor XII, SR-3576
- 3-[4-[[[(3-Methylphenyl)amino]carbonyl]amino]-1H-pyrazol-1-yl]-N-(3,4,5-trimethoxyphenyl)-benzamide
- JNK3 Inhibitor XII, SR-3576 - CAS 1164153-22-3 - Calbiochem
- 3-[4-(3-m-Tolyl-ureido)-pyrazol-1-yl]-N-(3,4,5-trimethoxy-phenyl)-benzamide
- JNK3 Inhibitor XII
- SR-3576 >=98% (HPLC)
- Benzamide, 3-[4-[[[(3-methylphenyl)amino]carbonyl]amino]-1H-pyrazol-1-yl]-N-(3,4,5-trimethoxyphenyl)-
- SR 3576, JNK3 inhibitor
- 1164153-22-3