Peramivir Trihydrate
CAS-Nr.
1041434-82-5
Englisch Name:
Peramivir Trihydrate
Synonyma:
PeraMivir Hydrate;eraMivir;S-021812;Preamivir;BCX-1812,RWJ-270201;Rapiacta trihydrate;BCX 1812 trihydrate;Peramivir Trihydrate;Peramivir Tirhydrate;Peramivir Impurity A
CBNumber:
CB22538918
Summenformel:
C15H30N4O5
Molgewicht:
346.43
MOL-Datei:
1041434-82-5.mol
Peramivir Trihydrate Eigenschaften
storage temp.
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
L?slichkeit
H2O : 6.6 mg/mL (17.26 mM; Need ultrasonic)
Aggregatzustand
Powder
Farbe
White to off-white
Optische Rotation
[α]/D -125 to -145°, c =0.1 in H2O
InChIKey
DLIKIAYLVAIOME-KAJZLETJNA-N
SMILES
[C@H]([C@]1([H])[C@@H]([C@@H](C(=O)O)C[C@H]1NC(N)=N)O)(NC(=O)C)C(CC)CC.O |&1:0,1,3,4,9,r|
Sicherheit
Risiko- und Sicherheitserkl?rung
Gefahreninformationscode (GHS)
Bildanzeige (GHS)
Alarmwort
Warnung
Gefahrenhinweise
Code
Gefahrenhinweise
Gefahrenklasse
Abteilung
Alarmwort
Symbol
P-Code
H317
Kann allergische Hautreaktionen verursachen.
Sensibilisierung der Haut
Kategorie 1A
Warnung
src="/GHS07.jpg" width="20" height="20" />
P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319
Verursacht schwere Augenreizung.
Schwere Augenreizung
Kategorie 2
Warnung
src="/GHS07.jpg" width="20" height="20" />
P264, P280, P305+P351+P338,P337+P313P
Sicherheit
P280
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P305+P351+P338
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.
Peramivir Trihydrate Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Peramivir Trihydrate is a trihydrate of the anti-infection agent Peramivir Trihydrate which is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM.[1] The IC50 for Peramivir Trihydrate
Definition
ChEBI: A hydrate that is the trihydrate form of peramivir. Used for the treatment of acute uncomplicated influenza in patients 18 years and older who have been symptomatic for no more than two days.
in vitro
Peramivir trihydrate (0.3125-40 μM, 4 h) has nontoxicity to macrophage.
Peramivir trihydrate (2-10 μM, 6-12 h) inhibits cytokine release in LPS-induced hPBMCs.
Peramivir Trihydrate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Peramivir Trihydrate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 277)Lieferanten
China 256
India 6
South Korea 1
United Kingdom 1
United States 13
Global 277
Peramivir Trihydrate
BCX 1812 trihydrate
Rapiacta trihydrate
RWJ 270201 trihydrate
(1S,2S,3R,4R)-3-[(1S)-1-(Acetylamino)-2-ethylbutyl]-4-[(aminoiminomethyl)amino]-2-hydroxycyclopentanecarboxylic acid hydrate
PeraMivir trihydrate/3(R)-[1(S)-AcetaMido-2-ethylbutyl]-4(R)-guanidino-2(S)-hydroxycyclopentane-1(S)-carboxylic acid
eraMivir
(1S,2S,3R,4R)-3-((S)-1-acetamido-2-ethylbutyl)-4-guanidino-2-hydroxycyclopentanecarboxylic acid trihydrate
BCX-1812,RWJ-270201
S-021812
Peramivir Tirhydrate
(1S,2S,3R,4R)-3-[(1S)-1-(Acetylamino)-2-ethylbutyl]-4-[(aminoiminomethyl)amino]-2-hydroxycyclopentanecarboxylic acid trihydrate
RWJ 270201 TRIHYDRATE;BCX 1812 TRIHYDRATE
Cyclopentanecarboxylic acid, 3-[(1S)-1-(acetylamino)-2-ethylbutyl]-4-[(aminoiminomethyl)amino]-2-hydroxy-, hydrate (1:3), (1S,2S,3R,4R)-
(1S,2S,3R,4R)-3-((S)-1-acetamido-2-ethylbutyl)-4-guanidino-2-hydroxycyclopentane-1-carboxylic acid trihydrate
Peramivir Impurity A
Peramivir Trihydrate (RWJ-270201
Paramivir trihydrate
PeraMivir Hydrate
Preamivir
(1S,2S,3R,4R)-3-[(1S)-1-(acetylamino)-2-ethylbutyl]-4-[(aminoiminomethyl)amino]-2-hydroxy-Cyclopentanecarboxylic acid hydrate (1:3)
Paramivir impurity A
Panamivir trihydrate
Propanamide, 2,2'-(1,2-diazenediyl)bis(N-(2-hydroxyethyl)-2-methyl-
1041434-82-5
C15H36N4O8
C15H28N4O43H2O
C15H34N4O7
Inhibitors
API
1041434-82-5