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Poziotinib (HM781-36B)

Poziotinib (HM781-36B) Struktur
1092364-38-9
CAS-Nr.
1092364-38-9
Englisch Name:
Poziotinib (HM781-36B)
Synonyma:
Poziotinib;CS-1788;NOV120101;pozytinib;Pozzi for;HM781-36B);UNII-OEI6OOU6IK;Poziotinib(NOV120101;Poziotinib HM-781368;poziotinib(HM-78136B)
CBNumber:
CB22668103
Summenformel:
C23H21Cl2FN4O3
Molgewicht:
491.34
MOL-Datei:
1092364-38-9.mol

Poziotinib (HM781-36B) Eigenschaften

Schmelzpunkt:
187 - 190° C
Siedepunkt:
629.7±55.0 °C(Predicted)
Dichte
1.409±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer, Under inert atmosphere
L?slichkeit
Chloroform (Slightly), DMSO (Slightly, Sonicated)
pka
5.35±0.30(Predicted)
Aggregatzustand
Solid
Farbe
White to Pale Beige
CAS Datenbank
1092364-38-9

Sicherheit

Poziotinib (HM781-36B) Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Poziotinib is a TKI that covalently and irreversibly inhibits EGFR and HER2, and is unique because of its small terminal group and flexible quinazoline core. Its small size and flexibility allow it to evade the steric hindrance which affects other EGFR TKIs [138].

Verwenden

Poziotinib can be used to inhibit the growth of cancer cells.

Poziotinib (HM781-36B) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

6-Quinazolinol, 4-[(3,4-dichloro-2-fluorophenyl)amino]-7-methoxy-, 6-acetate 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate 1-[4-[[(4-Methylphenyl)sulfonyl]oxy]-1-piperidinyl]-2-propen-1-one 4-(3,4-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-ol 3,4-Dichloro-2-fluoroaniline Acryloylchlorid

Downstream Produkte

Poziotinib (HM781-36B) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 200)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
HangZhou RunYan Pharma Technology Co.,LTD.
+8618882027439
 sales2@runyanpharma.com China 302 58
Shanghai Daken Advanced Materials Co.,Ltd 		+86-2158073036
info@dakenam.com China 19886 58
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 33024 60
career henan chemical co 		+86-0371-86658258 +8613203830695
 sales@coreychem.com China 29856 58
TianYuan Pharmaceutical CO.,LTD 		+86-755-23284190 13684996853
sales@tianpharm.com CHINA 304 58
Shenzhen Excellent Biotech Co., Ltd. 		13480692018
ramyan@ex-biotech.com CHINA 954 58
Jurong Coupling Biotechnology Co., Ltd. 		13656108824
coupling278191416@hotmail.com CHINA 184 58
TargetMol Chemicals Inc. 		+17819995354
 marketing@targetmol.com United States 32281 58
Hubei Ipure Biology Co., Ltd 		+8613367258412
 ada@ipurechemical.com China 10244 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226
 sales@hzclap.com CHINA 6312 58

1092364-38-9()Verwandte Suche:

  • 1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one
  • UNII-OEI6OOU6IK
  • 1-(4-((4-((3,4-dichloro-2-fluorophenyl)aMino)-7- Methoxyquinazolin-6-yl)oxy)piperidin-1-yl)prop-2-en-1-one
  • 1-[4-[4-(3,4-dichloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl]oxypiperidin-1-yl]prop-2-en-1-one
  • poziotinib(HM-78136B)
  • NOV120101
  • 1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one Poziotinib
  • HM781-36B)
  • Poziotinib(NOV120101
  • CS-1788
  • HM781-36B; NOV120101; NOV-120101; NOV 120101; POZIOTINIB
  • Poziotinib (HM781-37B)
  • 2-Propen-1-one, 1-[4-[[4-[(3,4-dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-
  • Poziotinib HM-781368
  • pozytinib
  • Pozzi for
  • 3-Pyridinecarbonitrile,6-fluoro-9-nitro-
  • Poziotinib
  • Poziotinib (HM-781-36)
  • Poziotinib, 10 mM in DMSO
  • 1092364-38-9
  • C23H21Cl2FN4O3
  • Inhibitors
  • API
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