Methylisothiocyanat
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Methylisothiocyanat Eigenschaften
- Schmelzpunkt:
- 30-34 °C(lit.)
- Siedepunkt:
- 117-118 °C(lit.)
- Dichte
- 1.069 g/mL at 25 °C(lit.)
- Dampfdruck
- 21 mm Hg ( 20 °C)
- Brechungsindex
- nD37 1.5258
- Flammpunkt:
- 90 °F
- storage temp.
- 2-8°C
- L?slichkeit
- H2O: slightly soluble
- Aggregatzustand
- Low Melting Solid
- Farbe
- White to pale yellow
- Geruch (Odor)
- at 0.01 % in propylene glycol. pungent mustard horseradish
- Geruchsart
- pungent
- Biologische Quelle
- rabbit
- Wasserl?slichkeit
- 7.6 g/L
- Sensitive
- Moisture Sensitive
- Merck
- 14,6092
- JECFA Number
- 1884
- BRN
- 605319
- Specific Activity
- 19-25nmol/min·mg
- Stabilit?t:
- Stable. Incompatible with strong oxidizing agents, alcohols, strong bases, amines.
- InChIKey
- LGDSHSYDSCRFAB-UHFFFAOYSA-N
- LogP
- 1.3 at 20℃
- CAS Datenbank
- 556-61-6(CAS DataBase Reference)
- NIST chemische Informationen
- Methane, isothiocyanato-(556-61-6)
- EPA chemische Informationen
- Methyl isothiocyanate (556-61-6)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher | T,N | ||
---|---|---|---|
R-S?tze: | 23/25-34-43-50/53 | ||
S-S?tze: | 36/37-38-45-60-61 | ||
RIDADR | UN 2477 6.1/PG 1 | ||
WGK Germany | 3 | ||
RTECS-Nr. | PA9625000 | ||
F | 21 | ||
TSCA | Yes | ||
HazardClass | 6.1 | ||
PackingGroup | I | ||
HS Code | 29309090 | ||
Giftige Stoffe Daten | 556-61-6(Hazardous Substances Data) | ||
Toxizit?t | LD50 in rats, mice (mg/kg): 220, 110 orally; in rabbits (mg/kg): 33 dermally (Vernot); LD50 s.c. in mice: 0.05 g/kg (Klesse, Lukoschek) |
Bildanzeige (GHS) |
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Methylisothiocyanat Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R23/25:Giftig beim Einatmen und Verschlucken.R34:Verursacht Ver?tzungen.
R43:Sensibilisierung durch Hautkontakt m?glich.
R50/53:Sehr giftig für Wasserorganismen, kann in Gew?ssern l?ngerfristig sch?dliche Wirkungen haben.
S-S?tze Betriebsanweisung:
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.S38:Bei unzureichender Belüftung Atemschutzger?t anlegen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
S60:Dieses Produkt und sein Beh?lter sind als gef?hrlicher Abfall zu entsorgen.
S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.
Beschreibung
Methyl iso thio cyanate is the organo sulfur compound with the formula CH3N = C = S . This low melting colorless solid is a powerful lachrymator. As a precursor to a variety of valuable bioactive compounds, it is the most important organic iso thio cyanate in industry.Chemische Eigenschaften
Methyl isothiocyanate is a crystalline solid. Horseradish, acrid odor.Occurrence
Reported found in horseradish.Verwenden
Usually used to study the effect of pesticide Metam (methyl isothiocyanate is its active ingredient) in the streamside microbial communities of the upper Sacramento riverDefinition
ChEBI: An isothiocyanate having a methyl group attached to the nitrogen.Application
Solutions of MITC are used in agriculture as soil fumigants, mainly for protection against fungi and nematodes.MITC is a building block for the synthesis of 1,3,4 - thiadiazoles, which are heterocyclic compounds used as herbicides. Commercial products include "Spike", "Ustilan," and "Erbotan." Well known pharmaceuticals prepared using MITC include Zantac and Tagamet.
Reaktionen
A characteristic reaction is with amines to give methyl thioureas:CH3NCS + R2NH → R2NC(S)NHCH3
Other nucleophiles add similarly.
Allgemeine Beschreibung
A colorless liquid with a sharp odor. Lethal by inhalation of even small quantities of vapor. Does not have odor warning characteristics at low concentrations. Do not rely on the sense of smell to warn about the presence of vapors. Denser than water. Flash point below 20°F. May cause tearing and irritate the eyes, skin, nose and throat.Air & Water Reaktionen
Highly flammable. Methyl isothiocyanate reacts with water to form carbon dioxide and methylamine gases.Reaktivit?t anzeigen
Isocyanates and thioisocyanates, such as Methyl isothiocyanate, are incompatible with many classes of compounds, reacting exothermically to release toxic gases. Reactions with amines, aldehydes, alcohols, alkali metals, ketones, mercaptans, strong oxidizers, hydrides, phenols, and peroxides can cause vigorous releases of heat. Acids and bases initiate polymerization reactions in these materials. Some isocyanates react with water to form amines and liberate carbon dioxide. Polyurethanes are formed by the condensation reaction of diisocyanates with, for example, ethyl glycol.Hazard
Toxic by ingestion, strong irritant to eyesand skin.Health Hazard
Very toxic; probable human oral lethal dose is 50-500 mg/kg, or between 1 teaspoonful and 1 oz. for a 70 kg (150 lb.) person. Highly irritating to skin, mucous membrances, and eyes. Human oral minimum lethal dose: approximately 1 g/kg.Brandgefahr
(Non-Specific -- Pesticide, Solid, n.o.s.) Methyl isothiocyanate may burn, but does not ignite readily. Fire may produce irritating or poisonous gases. When heated Methyl isothiocyanate emits very dangerous cyanides and sulfur compounds. Do not store below -4F or at elevated temperatures. Keep away from sparks.Sicherheit(Safety)
MITC is a dangerous lachrymator as well as being poisonous.m?gliche Exposition
It is used as a soil fumigant. A mixture of methyl isothiocyanate and chlorinated C-3 hydrocarbons is used as a soil fumigant for control of weeds, fungi, insects, and nematodes.Environmental Fate
Soil. Though no products were reported, the reported half-life in soil is <14 days (Worthing and Hance, 1991).Chemical/Physical. Emits toxic fumes of nitrogen and sulfur oxides when heated to decomposition (Sax and Lewis, 1987).
Stoffwechselwegen
Methyl isothiocyanate is slowly decomposed in pure water, forming methylamine. It is metabolised in rats to the mercapturate via the glutathione conjugate which serves as a potential source of methyl isothiocyanate. Methyl isothiocyanate is reactive with cellular thiols and amines and its toxicity is associated with these reactions.Versand/Shipping
UN2477 Methyl isothiocyanate, Hazard class: 6.1; Labels: 6.1-Poison Inhalation Hazard, 3-Flammable liquid, Inhalation Hazard Zone B.Inkompatibilit?ten
Dust may form explosive mixture with air. Reacts with water, releasing carbon dioxide and methylamine gases. Unstable and reactive; sensitive to oxygen and to light. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, alcohols, strong bases, amines, water, heat and cold. Attacks iron, zinc and other metalsWaste disposal
In accordance with 40CFR 165 recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA officeMethylisothiocyanat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
ISOTHIOCYANATE, POLYMER-BOUND, 200-400
Bright red
Methylamin, gasf?rmig
Ethyl-chlorformiat
Kohlendisulfid
Downstream Produkte
Methylthioharnstoff
Thiamazol
4-METHYL-5-PYRIDIN-4-YL-4H-[1,2,4]TRIAZOLE-3-THIOL
1-Methyl-3-phenyl-2-thiourea
3H-1,2,4-Triazole-3-thione, 2,4-dihydro-5-(hydroxymethyl)-4-methyl- (9CI)
4-METHYL-1-(TRIFLUOROACETYL)-3-THIOSEMICARBAZIDE
N-methylthiatriazol-5-amine
N-(2-BROMOPHENYL)-N'-METHYLTHIOUREA
AKOS USSH-4110876
1H-Pyrrolo[1,2-c]imidazol-1-one,hexahydro-2-methyl-3-thioxo-(9CI)
Methylisothiocyanat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 216)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
---|---|---|---|---|---|
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21622 | 55 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28172 | 58 |
Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 |
sales@finerchem.com | China | 2955 | 58 |
Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 |
sales@amoychem.com | China | 6369 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22963 | 58 |
Standardpharm Co. Ltd. | 86-714-3992388 |
overseasales1@yongstandards.com | United States | 14332 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49730 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
factory@coreychem.com | China | 29804 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 15319487004 |
1015@dideu.com | China | 3969 | 58 |
SIMAGCHEM CORP | +86-5922680277 +86-13806087780 |
sale@simagchem.com | China | 17346 | 58 |
556-61-6(Methylisothiocyanat)Verwandte Suche:
Phenylisothiocyanat
Kresoxim-methyl
Methylacrylat
3',6'-Dihydroxy-5(oder 6)-isothiocyanatospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-on
Methylthiocyanat
Bensulfuron methyl
1,4-Diisothiocyanatobenzol
Methyl-4-hydroxybenzoat
Methylthenoat
Cyclohexylisothiocyanat
Ethylisothiocyanatoformiat
Isopropylisocyanat
Benzylisocyanat
Cyclohexylisocyanat
Thiophanat-methyl
3-Methylthiopropylisothiocyanat
Methyl
isopropylisothiocyanat
- vorlex201(nor-am)
- Vortex
- WN 12
- wn12
- METHYL ISOTHIOCYANATE FOR PROTEIN &
- METHYL-ISO-THIOCYANATE PESTANAL, 250 MG
- Methyl #niso-thiocyanate
- Methylisothiocyanate,98%
- methyl isothiocyanate (bsi,iso,jmaf)
- methyl isorhodanate
- methyl isorhodanide
- Isothiocyanic acid methyl
- caswellno573
- Degussa methyl isothiocyanate
- EP-161E
- epapesticidechemicalcode068103
- Isothiocyanate de methyle
- isothiocyanatedemethyle
- isothiocyanatedemethyle(french)
- isothiocyanato-methan
- iso-Tihiocyanatomethane
- Isotiocianato di metile
- isotiocianatodemetilo
- isotiocianatodimetile
- methane,isothiocyanato-
- Methyl thioisocyanate
- Methylisothiocyanaat
- methylisothiocyanaat(netherlands)
- Methyl-isothiocyanat
- methylisothiocyanat(denmark)
- Methylisothiokyanat
- methylisothiokyanat(czech)
- methylmustard
- Methylsenfoel
- methylthioisocyanate
- metileisotiocianato
- Morton EP-161E
- mortonep-161e
- Trapex
- trapex-40
- Trapexide
- Tropex
- Vorlex
- vorlex(nor-am)
- Methyl isothiocyanate,97%
- thyl isothiocyanate
- Isothiocyanic acid ester
- --- D/C 09 --- Methyl isothiocyanate 1g [556-61-6]
- Methyl isothiocyanate, AcroSeal, 97%
- Methyl isothiocyanate, 98%, SpcSeal
- Methyl isothiocyanate, 97% 100GR
- Methyl isothiocyanate, 97%, AcroSeal
- Methylisothi
- DKFZp781l14186
- p140-TrKA
- TRKA (440-end), active, GST tagged human
- MGC32848
- MT1A