Alfuzosin hydrochloride
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- CAS-Nr.
- 81403-68-1
- Englisch Name:
- Alfuzosin hydrochloride
- Synonyma:
- URION;XATRAL;Alfoten;MITTOVAL;Uroxatral;UROXANTRAL;Udon：xatral;SL-77,499-10;ALFUZOSIN HCL;Alfuzosin-d7 HCl
- CBNumber:
- CB8703590
- Summenformel:
- C19H28ClN5O4
- Molgewicht:
- 425.91
- MOL-Datei:
- 81403-68-1.mol
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Alfuzosin hydrochloride Eigenschaften
- Schmelzpunkt:
- 225°C
- storage temp.
- 2-8°C
- L?slichkeit
- DMSO: >10mg/mL
- pka
- 8.13(at 25℃)
- Aggregatzustand
- solid
- Farbe
- White to Off-White
- Merck
- 14,238
- InChI
- InChI=1S/C19H27N5O4.ClH/c1-24(8-5-7-21-18(25)14-6-4-9-28-14)19-22-13-11-16(27-3)15(26-2)10-12(13)17(20)23-19;/h10-11,14H,4-9H2,1-3H3,(H,21,25)(H2,20,22,23);1H
- InChIKey
- YTNKWDJILNVLGX-UHFFFAOYSA-N
- SMILES
- C12=C(N)N=C(N(C)CCCNC(=O)C3OCCC3)N=C1C=C(OC)C(OC)=C2.Cl
- CAS Datenbank
- 81403-68-1(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
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| R-S?tze: |
22 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
LT9965475 |
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| HS Code |
2934990002 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P330 |
Mund ausspülen. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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Alfuzosin hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
Beschreibung
Alfuzosin (SL-77499) (I), a quinazoline derivative which
is a uroselective alpha-1 adrenoreceptor antagonist, has been
developed and launched worldwide by Sanofi-Synthelabo,
for the treatment of benign prostate hyperplasia (BPH).
In November 2003, alfuzosin (I) was launched as an
extended release formulation in the US as Uroxatral utilizing
Skyepharma’s oral controlled release technology.
Chemische Eigenschaften
White to Off-White Solid
Verwenden
α1-Adrenoceptor antagonist structurally similar to Prozosin. Antihypertensive. Alfuzosin hydrochloride is used in treatment of benign prostatic hypertrophy.
Allgemeine Beschreibung
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Biologische Aktivit?t
Functionally uro-selective α 1 adrenoceptor antagonist that does not discriminate between α 1 subtypes. Inhibits increases in intraurethral pressure caused by phenylephrine-induced contraction by 81% with minor cardiovascular effects. Also relaxes corpus cavernosum tissue (pIC 50 = 7.64) in vitro .
Alfuzosin hydrochloride Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Alfuzosin hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 433)Lieferanten
81403-68-1()Verwandte Suche:
- Alfuzosin-d7 HCl
- Alfuzosin hydrochlorid
- Alfuzosin Hydrochloride (150 mg)
- Alfuzosin hydrochloride(Uroxatral)
- Uroxatral
- Alfuzosin hydrocholoride
- Uroxatral hydrochloride
- N-(3-((4-Amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino)-propyl)tetrahydrofuran-2-carboxamid
- N-[3-[(4-Amino-6,7-dimethoxy-2-quinazolynyl)methylamino]propyl]tetrahydro-2-furancarboxamide, SL-77,499-10, Mittoval, Urion, Xatral
- 2-Furancarboxamide, N-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-, hydrochloride
- Uroxatral hydrochloride, N-(3-((4-Amino-6,7-dimethoxy-2-quinazolinyl)methylamino)propyl)tetrahydro-2-furancarboxamide hydrochloride
- Udon：xatral
- alfuzosinehydrochloride
- SL-77,499-10
- MITTOVAL
- N-[3-[(4-AMINO-6,7-DIMETHOXY-2-QUINAZOLYNYL)METHYLAMINO]PROPYL]TETRAHYDRO-2-FURANCARBOXAMIDE
- n-[3-[(4-amino-6,7-dimethoxy-2-quinazolynyl)methylamino]propyl]tetrahydro-2-furancarboxamide hydrochloride
- XATRAL
- URION
- UROXANTRAL
- ALFUZOSIN HCL
- ALFUZOSIN HYDROCHLORIDE
- Alfoten
- N-[3-[(4-Amino-6，7-dimethoxy-2-quimdinyl)methyl-lamino]propyl]tetrahydro-2-furancarboxamide hydrochloride
- N-[3-[(4-Amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-2-furancarboxamidehydrochloride
- Alfuzosin hydrochloride (SL 77499-10)
- (RS)-N-[3-[(4-Amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino]propyl]tetrahydrofuran-2-carboxamide hydrochloride
- Alfuzosin for peak identification
- Alfuzosin for system suitability A
- N-[3-[(4-amino-6,7-dimethoxy-1,4-dihydroquinazolin-2-yl)-methylamino]propyl]-2-oxolanecarboxamide hydrochloride
- Alfuzosin Hydrochloride >
- Alfuzosin hydrochloride CRS
- N-[3-[(4-Amino-6,7-dimethoxy-2-quinazolynyl
- 4-Amino-6,7-dimethoxy-2-[methyl[3-[(tetrahydro-2-furoyl)amino]propyl]amino]quinazoline Hydrochloride
- Alfuzosin hydrochloride USP/EP/BP
- Afzosin hydrochloride impurity
- 81403-68-1 Alfuzosin Hydrochloride
- N-(3-((4-Amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino)propyl)tetrahydrofuran-2-carboxamide hydrochloride
- Alfuzosin HCl (SL 77499-10 HCl)
- Alfuzosin for peak identification (Y0001883)
- Alfuzosin for system suitability A (Y0001906)
- Alfuzosin HydrochlorideQ: What is
Alfuzosin Hydrochloride Q: What is the CAS Number of
Alfuzosin Hydrochloride Q: What is the storage condition of
Alfuzosin Hydrochloride Q: What are the applications of
Alfuzosin Hydrochloride
- TIANFU Alfuzosin hydrochloride
- Alfuzosin Hydrochloride (1012917)
- Alfuzosin HCl
(RS)-N-[3-[(4-Amino-6,7-dimethoxyquinazolin-2- yl)(methyl)amino]propyl]tetrahydrofuran-2-carboxamide hydrochloride
- SL 77499-10|||Alfuzosin HCl
- Alfuzosin hydrochloride, 10 mM in DMSO
- ALFUZOSIN HYDROCHLORIDE USP (NON-STERILE DRUG SUBSTANCE)
- 81403-68-1
- C19H27N5O4HCl
- H19H27N5O4HCl
- C19H27N5O4ClH
- Heterocycles
- Antihypertensive, Treatment of BPH
- Intermediates & Fine Chemicals
- Pharmaceuticals
- APIs
- Antihypertensive
