4-CHLORO-1-METHYL-1H-IMIDAZO[4,5-C]PYRIDINE
- CAS No.
- 50432-68-3
- Chemical Name:
- 4-CHLORO-1-METHYL-1H-IMIDAZO[4,5-C]PYRIDINE
- Synonyms
- 4-Chloro-1-methyl-imidazo[4,5-c]pyridine;4-CHLORO-1-METHYL-1H-IMIDAZO[4,5-C]PYRIDINE;1H-Imidazo[4,5-c]pyridine, 4-chloro-1-methyl-
- CBNumber:
- CB8418894
- Molecular Formula:
- C7H6ClN3
- Molecular Weight:
- 167.6
- MDL Number:
- MFCD00222101
- MOL File:
- 50432-68-3.mol
- MSDS File:
- SDS
Melting point | 168-170 °C(Solv: cyclohexane (110-82-7); ethyl acetate (141-78-6)) |
---|---|
Boiling point | 331.8±45.0 °C(Predicted) |
Density | 1.43±0.1 g/cm3(Predicted) |
storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
pka | 3.13±0.30(Predicted) |
Appearance | Light brown to black Solid |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H332-H335 |
Precautionary statements | P261-P280-P305+P351+P338 |
HS Code | 2933998090 |
4-CHLORO-1-METHYL-1H-IMIDAZO[4,5-C]PYRIDINE price More Price(28)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | C602088 | 4-Chloro-1-methyl-1H-imidazo[4,5-c]pyridine | 50432-68-3 | 50mg | $45 | 2021-12-16 | Buy |
Matrix Scientific | 072550 | 4-Chloro-1-methyl-1H-imidazo[4,5-c]pyridine 95+% | 50432-68-3 | 500mg | $58 | 2021-12-16 | Buy |
Biosynth Carbosynth | FC142178 | 4-Chloro-1-methyl-1H-imidazo[4,5-c]pyridine | 50432-68-3 | 10g | $782 | 2021-12-16 | Buy |
SynQuest Laboratories | 3H32-5-B6 | 4-Chloro-1-methyl-1H-imidazo[4,5-c]pyridine | 50432-68-3 | 1g | $425 | 2021-12-16 | Buy |
Biosynth Carbosynth | FC142178 | 4-Chloro-1-methyl-1H-imidazo[4,5-c]pyridine | 50432-68-3 | 5G | $460 | 2021-12-16 | Buy |
4-CHLORO-1-METHYL-1H-IMIDAZO[4,5-C]PYRIDINE Chemical Properties,Uses,Production
Synthesis
![4-CHLORO-1-H-IMIDAZO[4,5-C]PYRIDINE](/CAS/GIF/2770-01-6.gif)
2770-01-6

74-88-4
![4-CHLORO-1-METHYL-1H-IMIDAZO[4,5-C]PYRIDINE](/CAS/GIF/50432-68-3.gif)
50432-68-3
![4-Chloro-3-Methyl-3H-iMidazo[4,5-c]pyridine](/CAS/20150408/GIF/87034-78-4.gif)
87034-78-4
NaH (78 mg, 1.95 mmol, 60% w/w oil solution) was slowly added to a solution of 4-chloro-3H-imidazo[4,5-c]pyridine (100 mg, 0.65 mmol) in DMF (3 mL) at 0 °C under nitrogen protection. The reaction mixture was stirred at 0 °C for 40 min. Subsequently, iodomethane (277 mg, 1.95 mmol) was added at the same temperature. The reaction mixture was warmed to room temperature and stirring was continued for 2 hours. Upon completion of the reaction, the reaction was quenched with saturated aqueous NH4Cl solution and extracted with ethyl acetate (20 mL x 3). The organic layers were combined, dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. The residue was purified by preparative HPLC to afford 4-chloro-1-methyl-1H-imidazo[4,5-c]pyridine (58, 40.3 mg) and 4-chloro-3-methyl-3H-imidazo[4,5-c]pyridine (59, 41.0 mg), both yellow oils, respectively.LRMS (m/z): [M+H]+ calculated values 168.2, 170.2; measured values 168.0, 170.2.
References
[1] Patent: WO2016/101119, 2016, A1. Location in patent: Page/Page column 99; 100




4-CHLORO-1-METHYL-1H-IMIDAZO[4,5-C]PYRIDINE Preparation Products And Raw materials
4-CHLORO-1-METHYL-1H-IMIDAZO[4,5-C]PYRIDINE Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12397 | 58 |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30230 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49983 | 58 |
LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
Suzhou ARTK Medchem Co., Ltd. | +86-512-68323658 +86-18168183658 | sales1@artkmedchem.com | China | 39002 | 58 |
50432-68-3(4-CHLORO-1-METHYL-1H-IMIDAZO[4,5-C]PYRIDINE)Related Search:
1of3