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SC 144

SC 144 ??? ???
?? ??:
895158-95-9
???:
SC 144
???(??):
SC144;SC-144;SC 144;CS-805;SC 144; SC144;SC144;SC-144;SC 144;SC144, 10 mM in DMSO;2-(7-fluoropyrrolo[1,2-a]quinoxalin-4-yl)hydrazide;N'-(7-Fluoropyrrolo[1,2-a]quinoxalin-4-yl)pyrazine-2-carbohydrazide;N'-(7-Fluoropyrrolo[1,2-a]quinoxalin-4-yl)-2-pyrazinecarbohydrazide
CBNumber:
CB72666896
???:
C16H11FN6O
??? ??:
322.3
MOL ??:
895158-95-9.mol

SC 144 ??

??
1.53±0.1 g/cm3(Predicted)
?? ??
Store at -20°C
???
insoluble in EtOH; insoluble in H2O; ≥16.1 mg/mL in DMSO
??? ??
??
??? ??
??? ??
?? ?? (pKa)
8.87±0.43(Predicted)
??
Light yellow to yellow
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P280 ????/???/???/?????? ?????.
P301+P312 ??? ???? ??? ????(??)? ??? ????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

SC 144 C??? ??, ??, ??

??

SC144 is an orally active small-molecule gp130 inhibitor.

SC 144 ?? ?? ? ???

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SC 144 ?? ??

???( 95)?? ??
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 3358272972@qq.com China 3262 58

SC 144 ?? ??:

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