ChemicalBook >?? ???? >MMP-9/MMP-13???I
MMP-9/MMP-13???I
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MMP-9/MMP-13???I ??
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- 1.364±0.06 g/cm3(Predicted)
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- -20°C
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- DMSO ?? ???? ???
- ?? ?? (pKa)
- 9.38±0.23(Predicted)
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- White to off-white
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- Light Sensitive
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MMP-9/MMP-13???I C??? ??, ??, ??
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MMP-9/MMP-13 inhibitor I is a cell-permeable inhibitor of matrix metalloproteinases (MMPs) that most potently inhibits MMP-9 and MMP-13 (IC50s = 0.9 nM for both). It less effectively inhibits MMP-1, MMP-3, and MMP-7 (IC50s = 43, 23, and 920 nM, respectively). MMP-9/MMP-13 inhibitor I has been used to elucidate the roles of MMPs in biological systems, including tumor cell invasion and pathogenesis of P. falciparum.??
A piperazine-based, cell-permeable, and highly potent inhibitor of MMP-9 and MMP-13MMP-9/MMP-13???I ?? ?? ? ???
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MMP-9/MMP-13???I ?? ??
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