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RO5126766(CH5126766)

RO5126766(CH5126766) ??? ???
?? ??:
946128-88-7
???:
RO5126766(CH5126766)
???(??):
CH5126766;CKI-27;R-7304;CS-1469;VS-6766;Avutometinib;CH5126766-002;RO5126766(CH5126766);Ro 5126766, 10 mM in DMSO;N-[3-Fluoro-4-[[4-methyl-2-oxo-7-(2-pyrimidinyloxy)-2H-1-benzopyran-3-yl]methyl]-2-pyridinyl]-N′-methylsulfamide
CBNumber:
CB82712006
???:
C21H18FN5O5S
??? ??:
471.46
MOL ??:
946128-88-7.mol

RO5126766(CH5126766) ??

?? ?
690.8±65.0 °C(Predicted)
??
1.495±0.06 g/cm3(Predicted)
?? ??
Store at -20°C
???
insoluble in H2O; insoluble in EtOH; ≥35.7 mg/mL in DMSO
??? ??
??
?? ?? (pKa)
6.60±0.50(Predicted)
??
White to yellow
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
0
2 0

RO5126766(CH5126766) C??? ??, ??, ??

RO5126766(CH5126766) ?? ?? ? ???

???

Sulfamoyl Chloride

?? ??

RO5126766(CH5126766) ?? ??

???( 83)?? ??
??? ?? ??? ?? ?? ? ??
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RO5126766(CH5126766) ?? ??:

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