- SELEXIPAG interMediate
-
- $35.00 / 1kg
-
2024-03-23
- CAS:475086-75-0
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
- SELEXIPAG interMediate
-
- $2.00 / 1KG
-
2019-07-06
- CAS:475086-75-0
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 200KG
|
| | SELEXIPAG interMediate Basic information |
| Product Name: | SELEXIPAG interMediate | | Synonyms: | SELEXIPAG interMediate;Selexipag intermediates;1-Butanol, 4-[(5,6-diphenylpyrazinyl)(1-methylethyl)amino]-;1-Butanol, 4-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]-;4-[(5,6-Diphenylpyrazinyl)(1-methylethyl)amino]-1-butanol;-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-Butanol;Selexipag Impurity AQ: What is
Selexipag Impurity A Q: What is the CAS Number of
Selexipag Impurity A Q: What is the storage condition of
Selexipag Impurity A Q: What are the applications of
Selexipag Impurity A;Selexipag internate 1 | | CAS: | 475086-75-0 | | MF: | C23H27N3O | | MW: | 361.48 | | EINECS: | 813-799-3 | | Product Categories: | non-prostanoid prostacyclin (PGI2) receptor agonist;selexipag | | Mol File: | 475086-75-0.mol |  |
| | SELEXIPAG interMediate Chemical Properties |
| Melting point | 68 - 71°C | | Boiling point | 514.4±50.0 °C(Predicted) | | density | 1.112±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | solubility | Chloroform (Slightly), DMSO (Slightly) | | pka | 15.05±0.10(Predicted) | | form | Solid | | color | Pale Yellow to Light Yellow |
| | SELEXIPAG interMediate Usage And Synthesis |
| Uses | 4-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-butanol is a diphenylpyrazine derivative which belongs to a class of prostacyclin receptor agonists. It is an impurity of Selexipag (S253150) that is a potential drug for the treatment of various vascular disorders such as pulmonary arterial hypertension and arteriosclerosis obliterans. | | Application | Selexipag interMediate is a synthetic organic compound that is used as an intermediate in the synthesis of oxychloride. It is an oxychloride with a nucleophilic substitution reaction. The reaction proceeds selectively at the phosphorus atom and gives high yield. The reactivity of 4-[(5,6-diphenylpyrazin-2-yl)(propan-2-yl)amino]butan-1-ol is enhanced by the use of n butanol, which also acts as a solvent for the reaction. The product can be purified by filtration or recrystallization from hexane with piperazine as a reagent. |
| | SELEXIPAG interMediate Preparation Products And Raw materials |
|