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| | 3''-AMINO-2''-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID Basic information |
| Product Name: | 3''-AMINO-2''-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID | | Synonyms: | 3''-AMINO-2''-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID;Eltrombopag Intermediate 2;EltroMbopag I;3-(3-aMino-2-hydroxyphenyl)benzoic acid;[1,1'-Biphenyl]-3-carboxylic acid, 3'-aMino-2'-hydroxy-;3''-AMINO-2''-HYDROXY-BIPHENYL-3-CARBOXYLIC;Eltrombopag olamine Intermediate 1;3'-Amino-2'-hydroxybiphenyl-3-carboxylicAcid> | | CAS: | 376592-93-7 | | MF: | C13H11NO3 | | MW: | 229.23 | | EINECS: | 814-404-7 | | Product Categories: | 376592-93-7 | | Mol File: | 376592-93-7.mol |  |
| | 3''-AMINO-2''-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID Chemical Properties |
| Melting point | 222 °C(dec.) | | Boiling point | 474.8±45.0 °C(Predicted) | | density | 1.364 | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | DMSO (Slightly), Methanol (Slightly, Heated) | | form | Solid | | pka | 3.99±0.10(Predicted) | | color | Pale Yellow to Light Brown | | InChI | InChI=1S/C13H11NO3/c14-11-6-2-5-10(12(11)15)8-3-1-4-9(7-8)13(16)17/h1-7,15H,14H2,(H,16,17) | | InChIKey | ZXLYSSHNDUXXIN-UHFFFAOYSA-N | | SMILES | C1(C2=CC=CC(N)=C2O)=CC=CC(C(O)=O)=C1 |
| | 3''-AMINO-2''-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID Usage And Synthesis |
| Uses | 3’-Amino-2’-Hydroxy-[1,1’]Biphenyl-3-carboxylic Acid is used in the synthesis of monoethanolamine salts. A hydrazine cleavage product from Eltrombopag (E508000), an agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia |
| | 3''-AMINO-2''-HYDROXY-BIPHENYL-3-CARBOXYLIC ACID Preparation Products And Raw materials |
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