金石蠶苷
| 中文名稱 | 金石蠶苷 |
|---|---|
| 中文同義詞 | 金石蠶苷;金石蠶甙;金石蠶苷(標(biāo)準(zhǔn)品);金石蠶苷 (金石蠶甙);POLIUMOSIDE 金石蠶苷;金石蠶甙對照品,;金石蠶苷, 來源于廣東紫珠;金石蠶苷(對照品) |
| 英文名稱 | 2-(3,4-Dihydroxyphenyl)ethyl 3-O,6-O-bis(α-L-rhamnopyranosyl)-4-O-[(E)-3-(3,4-dihydroxyphenyl)propenoyl]-β-D-glucopyranoside |
| 英文同義詞 | 2-(3,4-Dihydroxyphenyl)ethyl 3-O,6-O-bis(α-L-rhamnopyranosyl)-4-O-[(E)-3-(3,4-dihydroxyphenyl)propenoyl]-β-D-glucopyranoside;Poliumoside;6-(3,4-Dihydroxyphenethoxy)-5-hydroxy-4-((3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)me;O-6-Deoxy-alpha-L-mannopyranosyl-(1-3)-O-[6-deoxy-alpha-L-mannopyranosyl-(1-6)]-beta-D-glucopyranoside 2-(3,4-dihydroxyphenyl)ethyl 4-[3-(3,4-dihydroxyphenyl)-2-propenoate];[6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-4-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy-2-[(3,4,5-trihydroxy-6-methyloxan-2-yl)oxymethyl]oxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate;Poliumoside, 98%, from Callicarpa kwangtungensis Chun;β-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl O-6-deoxy-α-L-mannopyranosyl-(1→3)-O-[6-deoxy-α-L-mannopyranosyl-(1→6)]-, 4-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate];[(2R,3R,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-4-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate |
| CAS號 | 94079-81-9 |
| 分子式 | C35H46O19 |
| 分子量 | 770.73 |
| EINECS號 | |
| 相關(guān)類別 | 對照品;植提標(biāo)準(zhǔn)品;中藥對照品;標(biāo)準(zhǔn)品;植物提取物;標(biāo)準(zhǔn)品-對照品;chemical reagent;pharmaceutical intermediate;精細(xì)化工;分析試劑標(biāo)準(zhǔn)品;標(biāo)準(zhǔn)品-中藥標(biāo)準(zhǔn)品;標(biāo)準(zhǔn)品 -中藥標(biāo)準(zhǔn)品;其它酚類;標(biāo)準(zhǔn)品，對照品;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract |
| Mol文件 | 94079-81-9.mol |
| 結(jié)構(gòu)式 |  |
金石蠶苷 性質(zhì)
| 沸點 | 1023.2±65.0 °C(Predicted) |
|---|---|
| 密度 | 1.62 |
| 儲存條件 | 2-8°C |
| 溶解度 | DMSO : 100 mg/mL (129.75 mM; 需要超聲) 乙醇 : 50 mg/mL (64.87 mM; 需要超聲) |
| 形態(tài) | 粉末 |
| 酸度系數(shù)(pKa) | 9.31±0.10(Predicted) |
| 顏色 | 白色 |
| InChIKey | YMWRMAOPKNYHMZ-NTKGBUBXNA-N |
Poliumoside對于晚期糖基化終產(chǎn)物的形成有顯著抑制作用，IC50值為19.69 μM。 在大鼠晶狀體醛糖還原酶測定試驗中，發(fā)現(xiàn) Poliumoside對rat lens aldose reductase(RLAR)表現(xiàn)出抑制作用，IC50值為8.47 μM。
藥理藥效:散瘀止血，消腫止痛。 葉:用于吐血，咯血，衄血，便血；外用治療外傷出血。
| Target | Value |
|
RLAR
() | 8.47 μM |
Poliumoside inhibits AGE formation and RLAR, with IC
50
s of 19.69, and 8.47 μM, respectively.
Poliumoside (5-30 μM; 3 h) inhibits AAPH-induced hemolysis of rat red blood cells in vitro.
Poliumoside (12.5-100 μM; pretreated 2 h) inhibits the release of TNF-α and IL-6 in LPS-induced RAW 264.7?cells.
Poliumoside inhibits vessel dilation in larval zebrafish.
化學(xué)性質(zhì)
類白色結(jié)晶粉末，溶于水，來源于廣東紫珠。用途
金石蠶苷具有抗菌消炎抗病毒作用。用途
用于含量測定/鑒定/藥理實驗等。藥理藥效:散瘀止血，消腫止痛。 葉:用于吐血，咯血，衄血，便血；外用治療外傷出血。
安全信息
| 海關(guān)編碼 | 29389090 |
|---|
| 更新日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
|---|---|---|---|---|---|
| 2025/05/22 | HY-N0033 | 金石蠶苷 Poliumoside | 94079-81-9 | 5 mg | 1046元 |
| 2025/05/22 | HY-N0033 | 金石蠶苷 Poliumoside | 94079-81-9 | 10mg | 1674元 |